Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 14/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.63 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.63 |
| ▸ | GC | P02774 | 1/20 | 0.63 |
| ▸ | PGR | P06401 | 1/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.63 |
| ▸ | RXRA | P19793 | 1/20 | 0.63 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.63 |
| ▸ | CNR1 | P21554 | 1/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.63 |
| ▸ | HTR2C | P28335 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.63 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.63 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9009943 | 1.00 | VDR (1.00) | VDRMAPTNR1I2ABCB11GC | |
| SCHEMBL5983246 | 1.00 | VDR (1.00) | VDRMAPTNR1I2ABCB11GC | |
| SCHEMBL5982347 | 1.00 | VDR (1.00) | VDRMAPTNR1I2ABCB11GC | |
| SCHEMBL5983382 | 1.00 | VDR (1.00) | VDRMAPTNR1I2ABCB11GC | |
| SCHEMBL9010871 | 0.94 | VDR (0.89) | VDR | |
| SCHEMBL9010877 | 0.94 | VDR (0.89) | VDR | |
| SCHEMBL14107800 | 0.93 | VDR (0.87) | VDRMAPTNR1I2ABCB11GC | |
| SCHEMBL13993776 | 0.90 | VDR (0.82) | VDRMAPTNR1I2ABCB11GC | |
| SCHEMBL13993784 | 0.90 | VDR (0.82) | VDRMAPTNR1I2ABCB11GC | |
| SCHEMBL13993789 | 0.90 | VDR (0.82) | VDRMAPTNR1I2ABCB11GC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188064-B2 | Reducing cell differentiation of adipocyte; reducing body fat | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-05-29 | — | — | US | disclosed |
| US-8188064-B2 | Reducing cell differentiation of adipocyte; reducing body fat | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-05-29 | — | — | US | disclosed |
| US-7745404-B2 | Use of calcitonin and calcitonin-like peptides to treat and prevent multiple sclerosis | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-06-29 | — | — | US | disclosed |
| US-7745404-B2 | Use of calcitonin and calcitonin-like peptides to treat and prevent multiple sclerosis | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-06-29 | — | — | US | disclosed |
| US-7566696-B2 | Use of calcitonin and calcitonin-like peptides to treat and prevent multiple sclerosis | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-07-28 | — | — | US | disclosed |
| US-7566696-B2 | Use of calcitonin and calcitonin-like peptides to treat and prevent multiple sclerosis | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-07-28 | — | — | US | disclosed |
| US-20080146491-A1 | USE OF CALCITONIN AND CALCITONIN-LIKE PEPTIDES TO TREAT AND PREVENT MULTIPLE SCLEROSIS | DELUCA HECTOR F | 2008-06-19 | — | — | US | disclosed |
| US-20080146491-A1 | USE OF CALCITONIN AND CALCITONIN-LIKE PEPTIDES TO TREAT AND PREVENT MULTIPLE SCLEROSIS | DELUCA HECTOR F | 2008-06-19 | — | — | US | disclosed |
| US-20070105774-A1 | Administering an appropriate dosage schedule of a bone calcium resorption inhibitor like alendronate and a toxic dose of a vitamin D compounds like 1, alpha 25-dihydroxyvitamin D3 without developing hypercalcemia | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2007-05-10 | — | — | US | disclosed |
| US-20070105774-A1 | Administering an appropriate dosage schedule of a bone calcium resorption inhibitor like alendronate and a toxic dose of a vitamin D compounds like 1, alpha 25-dihydroxyvitamin D3 without developing hypercalcemia | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105774-A1 | Administering an appropriate dosage schedule of a bone calcium resorption inhibitor like alendronate and a toxic dose of a vitamin D compounds like 1, alpha 25-dihydroxyvitamin D3 without developing hypercalcemia | CALCA, CALCRL, CYP24A1 | VDR 7/4885MAPT 2335/4885NR1I2 3136/4885 |
| US-20080146491-A1 | USE OF CALCITONIN AND CALCITONIN-LIKE PEPTIDES TO TREAT AND PREVENT MULTIPLE SCLEROSIS | CALCA, CALCB, CALCRL | VDR 5/4885MAPT 2497/4885NR1I2 3891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.