SCHEMBL9010059

SCHEMBL9010059

Cc1[c]c2c(cc1P(=O)(O)O)-c1ccccc1C2

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 1/20 0.35
MAOA P21397 2/20 0.35
HTR2C P28335 2/20 0.35
HTR2B P41595 2/20 0.35
CYP1A2 P05177 1/20 0.35
ADRA2A P08913 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
ALDH1A1 P00352 3/20 0.33
PPARG P37231 1/20 0.33
CYP2C9 P11712 1/20 0.33
TSHR P16473 1/20 0.33
GABRP O00591 1/20 0.33
GABRD O14764 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRB1 P18505 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
GABRA5 P31644 1/20 0.33
GABRA3 P34903 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL218437 0.77 ALDH1A1 (0.38) SRD5A2MAOAHTR2CHTR2BCYP1A2
SCHEMBL9010078 0.73 SRD5A2 (0.38) SRD5A2MAOAHTR2CHTR2BCYP1A2
Fluorene SCHEMBL27721231 0.68 MAOA (0.58) SRD5A2MAOAHTR2CHTR2BCYP1A2
SCHEMBL31742346 0.67 NPC1 (0.47) SRD5A2MAOAHTR2CHTR2BCYP1A2
SCHEMBL216980 0.66 ALDH1A1 (0.40) SRD5A2MAOAHTR2CHTR2BCYP1A2
SCHEMBL2690046 0.66 NPC1 (0.37) SRD5A2MAOAHTR2CHTR2BCYP1A2
SCHEMBL2046255 0.64 CYP1A2 (0.39) SRD5A2MAOAHTR2CHTR2BCYP1A2
SCHEMBL15522528 0.64 KDM4E (0.38) SRD5A2MAOAHTR2CHTR2BCYP1A2
SCHEMBL2958343 0.64 RAB9A (0.38) SRD5A2MAOAHTR2CHTR2BCYP1A2
SCHEMBL218323 0.64 MAOA (0.35) MAOAADRA2ASLC6A2SLC6A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0741145-A1 Olefin polymerization catalyst and process for producing polyolefin using the same SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-11-06 EP disclosed