Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 16/20 | 0.38 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9010402 | 0.83 | APLNR (0.38) | APLNR | |
| SCHEMBL9010408 | 0.81 | AGTR2 (0.55) | — | |
| SCHEMBL8633065 | 0.81 | AGTR2 (0.49) | — | |
| SCHEMBL8636224 | 0.80 | AGTR2 (0.46) | — | |
| SCHEMBL9010417 | 0.80 | AGTR2 (0.42) | — | |
| SCHEMBL9010377 | 0.77 | CHRM3 (0.37) | APLNR | |
| SCHEMBL9427433 | 0.75 | AGTR2 (0.41) | — | |
| SCHEMBL8656074 | 0.75 | CHRM3 (0.36) | APLNR | |
| SCHEMBL9010380 | 0.75 | CHRM3 (0.36) | APLNR | |
| SCHEMBL9428196 | 0.74 | AGTR2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521206-A | HYPOTENSIVE AGENTS, TREATMENT OF ATHEROSCLEROSIS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-05-28 | — | — | US | disclosed |