Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 7/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9010377 | 0.93 | CHRM3 (0.37) | APLNRCHRM3ALOX5HDAC6AGTR1 | |
| SCHEMBL8656074 | 0.92 | CHRM3 (0.36) | APLNRCHRM3ALOX5HDAC6AGTR1 | |
| SCHEMBL9010380 | 0.91 | CHRM3 (0.36) | APLNRCHRM3ALOX5HDAC6AGTR1 | |
| SCHEMBL9010419 | 0.83 | APLNR (0.38) | APLNR | |
| SCHEMBL7839692 | 0.77 | AGTR2 (0.50) | AGTR1AGTR2 | |
| SCHEMBL9010373 | 0.77 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL7839345 | 0.76 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL9010398 | 0.76 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL7839994 | 0.76 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL9092277 | 0.75 | AGTR1 (0.56) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521206-A | HYPOTENSIVE AGENTS, TREATMENT OF ATHEROSCLEROSIS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-05-28 | — | — | US | disclosed |