Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.52 |
| ▸ | DHODH | Q02127 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26012486 | 0.80 | CYP2D6 (0.62) | CYP2D6ALDH1A1SMN1; SMN2NPSR1GLO1 | |
| SCHEMBL26084789 | 0.79 | CYP2D6 (0.56) | CYP2D6ALDH1A1SMN1; SMN2NPSR1GLO1 | |
| SCHEMBL10314666 | 0.78 | CYP2D6 (0.71) | CYP2D6ALDH1A1SMN1; SMN2NPSR1GLO1 | |
| SCHEMBL11517764 | 0.77 | CYP2D6 (0.58) | CYP2D6ALDH1A1SMN1; SMN2NPSR1GLO1 | |
| SCHEMBL9326451 | 0.77 | CYP2D6 (0.58) | CYP2D6ALDH1A1SMN1; SMN2NPSR1GLO1 | |
| SCHEMBL26608078 | 0.75 | CYP2D6 (0.56) | CYP2D6ALDH1A1SMN1; SMN2NPSR1GLO1 | |
| SCHEMBL27790849 | 0.75 | CYP2D6 (1.00) | CYP2D6ALDH1A1SMN1; SMN2NPSR1GLO1 | |
| SCHEMBL1543791 | 0.75 | NPSR1 (0.58) | CYP2D6ALDH1A1SMN1; SMN2NPSR1GLO1 | |
| SCHEMBL1942274 | 0.74 | NPSR1 (0.62) | CYP2D6ALDH1A1SMN1; SMN2NPSR1GLO1 | |
| SCHEMBL15273109 | 0.74 | GLO1 (0.77) | CYP2D6ALDH1A1SMN1; SMN2NPSR1GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741320-A1 | Photothermographic Photosensitive Recording Material with Hugh Gradient | DU PONT DE NEMOURS (DEUTSCHLAND) GMBH (DE) | 1996-11-06 | — | — | EP | claimed |
| EP-2687515-A1 | METHOD FOR PRODUCING PYRAZOLECARBOXYLIC ACID DERIVATIVE | Shionogi & Co., Ltd. (JP) | 2014-01-22 | — | — | EP | disclosed |
| US-20140012013-A1 | METHOD FOR PRODUCING PYRAZOLE CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2014-01-09 | — | — | US | disclosed |
| EP-0741320-A1 | Photothermographic Photosensitive Recording Material with Hugh Gradient | DU PONT DE NEMOURS (DEUTSCHLAND) GMBH (DE) | 1996-11-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140012013-A1 | METHOD FOR PRODUCING PYRAZOLE CARBOXYLIC ACID DERIVATIVE | HSD11B1, HSD11B2, HSD17B1 | CYP2D6 137/4885ALDH1A1 115/4885SMN1; SMN2 4563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.