SCHEMBL901057

SCHEMBL901057

Nc1ccc(O)c(C2CCCCC2)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NUDT1 P36639 1/20 0.63
BACE1 P56817 1/20 0.63
HSP90AA1 P07900 1/20 0.54
ALDH1A1 P00352 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ACMSD Q8TDX5 2/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
PDE10A Q9Y233 1/20 0.41
KDM4E B2RXH2 3/20 0.41
MAPT P10636 2/20 0.41
GFER P55789 1/20 0.41
THRB P10828 2/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
ACHE P22303 2/20 0.39
TDO2 P48775 2/20 0.38
CHRNB2 P17787 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11097005 0.98 NUDT1 (0.61) NUDT1BACE1HSP90AA1ALDH1A1NPC1
SCHEMBL2873775 0.90 NUDT1 (0.50) NUDT1BACE1HSP90AA1ALDH1A1CA1
SCHEMBL2016444 0.85 NUDT1 (0.50) NUDT1BACE1HSP90AA1ALDH1A1NPC1
SCHEMBL22640382 0.82 NUDT1 (0.47) NUDT1BACE1HSP90AA1ALDH1A1NPC1
SCHEMBL25989709 0.82 CHRNB2 (0.55) NUDT1BACE1HSP90AA1ALDH1A1NPC1
SCHEMBL26309023 0.82 CHRNB2 (0.55) NUDT1BACE1HSP90AA1ALDH1A1NPC1
SCHEMBL26291025 0.82 CHRNB2 (0.55) NUDT1BACE1HSP90AA1ALDH1A1NPC1
SCHEMBL17774741 0.81 QDPR (0.51) NUDT1BACE1HSP90AA1CA1CA2
SCHEMBL1068254 0.80 NUDT1 (0.57) NUDT1BACE1HSP90AA1ACMSDKDM4E
SCHEMBL69755 0.80 NUDT1 (0.57) NUDT1BACE1HSP90AA1ALDH1A1ACMSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11866584-B2 High-refractive-index composition, high-refractive-index film, and method for manufacturing high-refractive-index film LG CHEM, LTD. (KR) 2024-01-09 US disclosed
CN-111801388-B High refractive composition, high refractive film, and method for manufacturing high refractive film 株式会社LG化学 2022-04-01 CN disclosed
CN-109715728-B Adducts and uses thereof 亨斯迈先进材料美国有限责任公司 2021-11-30 CN disclosed
US-20210095128-A1 HIGH-REFRACTIVE-INDEX COMPOSITION, HIGH-REFRACTIVE-INDEX FILM, AND METHOD FOR MANUFACTURING HIGH-REFRACTIVE-INDEX FILM LG CHEM, LTD. (KR) 2021-04-01 US disclosed
CN-111801388-A High refractive composition, high refractive film, and method for manufacturing high refractive film 株式会社LG化学 2020-10-20 CN disclosed
WO-2020060257-A1 HIGH-REFRACTIVE-INDEX COMPOSITION, HIGH-REFRACTIVE-INDEX FILM, AND METHOD FOR MANUFACTURING HIGH-REFRACTIVE-INDEX FILM 주식회사 엘지화학 2020-03-26 WO disclosed
US-20190211202-A1 ADDUCTS AND USES THEREOF HUNTSMAN ADVANCED MATERIALS AMERICAS LLC 2019-07-11 US disclosed
EP-3500627-A1 ADDUCTS AND USES THEREOF Huntsman Advanced Materials Americas LLC (US) 2019-06-26 EP disclosed
EP-2726530-B1 HYBRID EPOXY RESIN ADDUCTS BLUE CUBE IP LLC (US) 2018-09-12 EP disclosed
WO-2018035397-A1 ADDUCTS AND USES THEREOF HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2018-02-22 WO disclosed
US-5241021-A Reacting isocyanate with alkoxylated epoxy resin adducts and one or more compounds having active hydrogens; blowing agents THE DOW CHEMICAL COMPANY (US) 1993-08-31 US disclosed
US-5235008-A Curable THE DOW CHEMICAL COMPANY (US) 1993-08-10 US disclosed
EP-0478918-A2 Adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1992-04-08 EP disclosed
EP-0469492-A2 Polymer modified adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1992-02-05 EP disclosed
US-4820798-A Cyanate functional maleimide thermosetting composition THE DOW CHEMICAL COMPANY (US) 1989-04-11 US disclosed
US-4820797-A ACETYLENIC COPOLYMERS THE DOW CHEMICAL COMPANY (US) 1989-04-11 US disclosed
US-4769440-A FLEXIBILITY THE DOW CHEMICAL COMPANY (US) 1988-09-06 US disclosed
US-4731426-A Polymerization product from cyanate functional maleimide THE DOW CHEMICAL COMPANY (US) 1988-03-15 US disclosed
US-4683276-A CASTING, LAMINATION, COATING THE DOW CHEMICAL COMPANY (US) 1987-07-28 US disclosed
US-4680378-A Cyanate functional maleimide and polyamine copolymer THE DOW CHEMICAL COMPANY (US) 1987-07-14 US disclosed