Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MDM4 | O15151 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3531806 | 0.83 | GAA (0.61) | RAB9ASMN1; SMN2ALDH1A1NPC1GAA | |
| SCHEMBL7027104 | 0.80 | NPC1 (0.57) | RAB9ASMN1; SMN2ALDH1A1NPC1PKM | |
| SCHEMBL2090351 | 0.78 | GAA (0.52) | RAB9ASMN1; SMN2ALDH1A1NPC1GAA | |
| SCHEMBL27683406 | 0.76 | L3MBTL1 (0.55) | RAB9ASMN1; SMN2ALDH1A1NPC1GAA | |
| SCHEMBL17670950 | 0.76 | L3MBTL1 (0.58) | RAB9ASMN1; SMN2ALDH1A1NPC1PKM | |
| SCHEMBL11370989 | 0.75 | HDAC1 (0.54) | RAB9ASMN1; SMN2ALDH1A1NPC1PKM | |
| SCHEMBL9821286 | 0.74 | RAB9A (0.48) | RAB9ASMN1; SMN2ALDH1A1NPC1GAA | |
| SCHEMBL103123 | 0.74 | RAB9A (0.61) | RAB9ASMN1; SMN2ALDH1A1NPC1GAA | |
| Pronamide SCHEMBL2045136 | 0.73 | RAB9A (0.47) | RAB9ANPC1GAAPKMKMT2A | |
| Pronamide SCHEMBL55124 | 0.73 | RAB9A (0.47) | RAB9ANPC1GAAPKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547984-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1996-08-20 | — | — | US | disclosed |
| US-5529978-A | FUNGICIDE | ROHM AND HAAS COMPANY (US) | 1996-06-25 | — | — | US | disclosed |
| US-5344978-A | Fungicides | ROHM AND HAAS COMPANY (US) | 1994-09-06 | — | — | US | disclosed |
| US-5196046-A | N-acetonyl-substituted-amides | ROHM AND HAAS COMPANY (US) | 1993-03-23 | — | — | US | disclosed |
| EP-0170498-B1 | N-ACETONYL-SUBSTITUTED-AMIDES, COMPOSITIONS CONTAINING THEM AND THEIR USE IN COMBATING FUNGI | ROHM AND HAAS COMPANY (US) | 1991-09-11 | — | — | EP | disclosed |
| US-4863940-A | N-acetonyl-substituted amides and phytopathogenic fungicidal use thereof | ROHM AND HAAS (US) | 1989-09-05 | — | — | US | disclosed |
| EP-0170498-A2 | N-acetonyl-substituted-amides, compositions containing them and their use in combating fungi | ROHM AND HAAS COMPANY (US) | 1986-02-05 | — | — | EP | disclosed |