SCHEMBL9010870

SCHEMBL9010870

OC(COCC(F)(F)F)=C(c1ccccc1)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
CES1 P23141 2/20 0.37
F2 P00734 1/20 0.35
PLAU P00749 1/20 0.35
ELANE P08246 1/20 0.35
MAPK1 P28482 3/20 0.33
LMNA P02545 3/20 0.33
HTT P42858 2/20 0.33
HIF1A Q16665 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
POLB P06746 2/20 0.33
MLYCD O95822 1/20 0.33
ESR1 P03372 1/20 0.33
FABP7 O15540 1/20 0.32
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
MEN1 O00255 1/20 0.31
S1PR2 O95136 1/20 0.31
S1PR4 O95977 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8621299 0.77 ALDH1A1 (0.42) ALDH1A1CES1F2PLAUELANE
SCHEMBL4342386 0.75 ALDH1A1 (0.49) ALDH1A1CES1MAPK1LMNAHIF1A
SCHEMBL23698003 0.66 CES1 (0.50) ALDH1A1CES1F2LMNAL3MBTL1
SCHEMBL9056053 0.66 CES1 (0.50) ALDH1A1CES1F2L3MBTL1POLB
SCHEMBL8461140 0.66 CES1 (0.50) ALDH1A1CES1F2L3MBTL1POLB
SCHEMBL9115831 0.66 MAPK1 (0.58) ALDH1A1F2PLAUELANEMAPK1
SCHEMBL28449348 0.65 CES1 (0.48) ALDH1A1CES1MAPK1LMNAHTT
SCHEMBL8625967 0.63 MAOA (0.36) ALDH1A1CES1MAPK1LMNAHIF1A
SCHEMBL28271260 0.63 CES1 (0.46) ALDH1A1CES1MAPK1LMNAHTT
SCHEMBL8157722 0.63 ALDH1A1 (0.61) ALDH1A1CES1LMNAPOLBNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0507204-B1 Liquid crystal device, display apparatus using same and display method using same CANON KK (JP) 1996-11-20 EP disclosed
US-5268783-A Liquid crystal device including a polymer having a surface energy of at most 25 dyn/cm, display apparatus using same and display method using same CANON KABUSHIKI KAISHA (JP) 1993-12-07 US disclosed
EP-0507204-A1 Liquid crystal device, display apparatus using same and display method using same CANON KABUSHIKI KAISHA (JP) 1992-10-07 EP disclosed