Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.36 |
| ▸ | MAOB | P27338 | 5/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | MGMT | P16455 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8621299 | 0.84 | ALDH1A1 (0.42) | MAOAMAOBMAPK1HIF1ACES1 | |
| SCHEMBL8624256 | 0.80 | MAOA (0.33) | MAOAMAOBSMN1; SMN2 | |
| SCHEMBL5030638 | 0.80 | MAOA (0.33) | MAOAMAOBMAPK1HIF1ACES1 | |
| SCHEMBL7791505 | 0.78 | MAOA (0.41) | MAOAMAOBMAPK1CES1ALDH1A1 | |
| SCHEMBL3752087 | 0.76 | MAOA (0.50) | MAOAMAOBMAPK1CES1CDK1 | |
| SCHEMBL8623551 | 0.73 | MAOA (0.38) | MAOAMAOBCES1CDK1CCNB1 | |
| SCHEMBL194628 | 0.73 | ALDH1A1 (0.44) | MAOAMAOBALDH1A1LMNAPOLB | |
| SCHEMBL7792771 | 0.73 | MAOA (0.40) | MAOAMAOBMAPK1CES1ALDH1A1 | |
| SCHEMBL27591269 | 0.72 | MAOA (0.42) | MAOAMAOBMAPK1HIF1ACES1 | |
| SCHEMBL5012369 | 0.71 | MAOA (0.39) | MAOAMAOBCES1NPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786434-A | A CURABLE COPOLYMER COMPRISING A DIALKYLACRYLAMIDE OR METHACRYLAMIDE, A VINYLLACTAM, A BIS(SILICON-CONTAINING ALKYL)FUMARATE MONOMERS; RADIATION TRANSPARENT, HIGH OXYGEN PERMEABILITY | MENICON CO., LTD. (JP) | 1998-07-28 | — | — | US | disclosed |