Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 3/20 | 0.34 |
| ▸ | ACHE | P22303 | 3/20 | 0.34 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
| ▸ | GRN | P28799 | 2/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8156479 | 0.86 | GRN (0.45) | GRNSORT1 | |
| SCHEMBL8167643 | 0.84 | ALDH1A1 (0.33) | ERAP1ANO1GRNSORT1HTT | |
| SCHEMBL8060065 | 0.83 | HSD11B1 (0.36) | ERAP1ANO1HTTCYP2C19 | |
| SCHEMBL9010820 | 0.78 | SMN1; SMN2 (0.33) | HTTCYP2C19CNR2 | |
| SCHEMBL9010839 | 0.74 | ALDH1A1 (0.36) | ERAP1ANO1 | |
| SCHEMBL1591897 | 0.74 | POLB (0.46) | BCHEACHES1PR2 | |
| SCHEMBL7161750 | 0.74 | ALDH1A1 (0.34) | ERAP1ANO1GRNSORT1HTT | |
| SCHEMBL7027760 | 0.74 | ALDH1A1 (0.34) | ERAP1ANO1GRNSORT1HTT | |
| SCHEMBL8060000 | 0.74 | HSD11B1 (0.36) | ERAP1ANO1HTTL3MBTL1CA2 | |
| SCHEMBL8059015 | 0.73 | HSD11B1 (0.37) | ERAP1ANO1GRNSORT1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0170498-B1 | N-ACETONYL-SUBSTITUTED-AMIDES, COMPOSITIONS CONTAINING THEM AND THEIR USE IN COMBATING FUNGI | ROHM AND HAAS COMPANY (US) | 1991-09-11 | — | — | EP | claimed |
| EP-0170498-A2 | N-acetonyl-substituted-amides, compositions containing them and their use in combating fungi | ROHM AND HAAS COMPANY (US) | 1986-02-05 | — | — | EP | claimed |
| US-5547984-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1996-08-20 | — | — | US | disclosed |
| US-5529978-A | FUNGICIDE | ROHM AND HAAS COMPANY (US) | 1996-06-25 | — | — | US | disclosed |
| US-5196046-A | N-acetonyl-substituted-amides | ROHM AND HAAS COMPANY (US) | 1993-03-23 | — | — | US | disclosed |
| EP-0170498-B1 | N-ACETONYL-SUBSTITUTED-AMIDES, COMPOSITIONS CONTAINING THEM AND THEIR USE IN COMBATING FUNGI | ROHM AND HAAS COMPANY (US) | 1991-09-11 | — | — | EP | disclosed |
| US-4863940-A | N-acetonyl-substituted amides and phytopathogenic fungicidal use thereof | ROHM AND HAAS (US) | 1989-09-05 | — | — | US | disclosed |
| EP-0170498-A2 | N-acetonyl-substituted-amides, compositions containing them and their use in combating fungi | ROHM AND HAAS COMPANY (US) | 1986-02-05 | — | — | EP | disclosed |