SCHEMBL9010906

SCHEMBL9010906

CC(=O)C(=S)C(=O)ON1C(=O)CCC1=O

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 3/20 0.33
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.32
GLA P06280 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10889616 0.84 GLA (0.39) MGLLKMT2AATMGLA
SCHEMBL865136 0.79 MGLL (0.40) MGLLKMT2AATMGLA
SCHEMBL4618888 0.77 GLA (0.32) MGLLGLA
SCHEMBL17550003 0.77 KMT2A (0.38) MGLLKMT2AATMGLA
SCHEMBL73278 0.76 KMT2A (0.47) MGLLKMT2AATMGLA
SCHEMBL118685 0.74 PARL (0.41) MGLLKMT2AATM
SCHEMBL18510166 0.74 GLA (0.41) MGLLKMT2AATMGLA
SCHEMBL30699 0.74 GLA (0.41) MGLLKMT2AATMGLA
SCHEMBL30779753 0.74 GLA (0.41) MGLLKMT2AATMGLA
SCHEMBL22089478 0.73 MGLL (0.33) MGLLKMT2AATMGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5567432-A MEMBRANE ENCAPSULATED BY SYNTHETIC NEUMAMINIC ACID RESIDUE;RETICULOENDOTHELIAL SYSTEM SDG, INC. 1996-10-22 US disclosed