Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9011028 | 0.86 | TK1 (0.53) | TK1LMNATSHRALBPKM | |
| SCHEMBL15643543 | 0.84 | TK1 (0.66) | TK1POLB | |
| SCHEMBL14690119 | 0.82 | TK1 (0.59) | TK1LMNATSHRALBPKM | |
| SCHEMBL2379396 | 0.81 | POLB (0.56) | TK1LMNATSHRALBPKM | |
| SCHEMBL2295 | 0.81 | TK1 (0.63) | TK1POLB | |
| SCHEMBL25752530 | 0.81 | TK1 (0.70) | TK1POLB | |
| SCHEMBL316663 | 0.80 | TK1 (0.65) | TK1POLB | |
| SCHEMBL6379327 | 0.80 | TK1 (0.67) | TK1 | |
| SCHEMBL9201376 | 0.78 | POLB (0.63) | TK1LMNATSHRALBPKM | |
| SCHEMBL34209 | 0.78 | POLB (0.63) | TK1LMNATSHRALBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080292550-A1 | Fluorinated 3'-Deoxythymidine Derivatives, a Method for Their Preparation and Their Use | MAX-DELBRUECK-CENTRUM FUER MOLEKULARE MEDIZIN (DE) | 2008-11-27 | — | — | US | disclosed |
| EP-1874789-A1 | FLUORINATED 3'-DEOXYTHYMIDINE DERIVATIVES, A METHOD FOR THEIR PREPARATION AND THEIR USE | MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN (DE) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006114336-A1 | FLUORINATED 3'-DEOXYTHYMIDINE DERIVATIVES, A METHOD FOR THEIR PREPARATION AND THEIR USE | Max-Delbrück-Centrum für Molekulare Medizin (DE) | 2006-11-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080292550-A1 | Fluorinated 3'-Deoxythymidine Derivatives, a Method for Their Preparation and Their Use | EEF1A2, DUT, CYP4F2 | TK1 113/4885LMNA 1927/4885TSHR 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.