Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9011228 | 0.93 | HSP90AA1 (0.45) | NPSR1ALDH1A1KDM4EMAPTTSHR | |
| SCHEMBL9011007 | 0.86 | KMT2A (0.45) | NPSR1ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL7813608 | 0.82 | MAPT (0.57) | NPSR1ALDH1A1MAPTTSHRLMNA | |
| SCHEMBL7810031 | 0.82 | MAPT (0.49) | NPSR1ALDH1A1HPGDMAPTTSHR | |
| SCHEMBL7810164 | 0.80 | MEN1 (0.58) | NPSR1ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL7814258 | 0.80 | TSHR (0.61) | NPSR1ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL7813606 | 0.78 | MAPT (0.58) | NPSR1ALDH1A1MAPTTSHRLMNA | |
| SCHEMBL7810027 | 0.78 | MAPT (0.50) | NPSR1ALDH1A1KDM4EMAPTTSHR | |
| SCHEMBL7813660 | 0.78 | MAPT (0.56) | ALDH1A1MAPTTSHRUSP2MEN1 | |
| SCHEMBL9011142 | 0.76 | MAPT (0.42) | ALDH1A1KDM4EMAPTTSHRUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |