Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | USP2 | O75604 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7817566 | 0.80 | MAPT (0.55) | MAPTALDH1A1GAAKMT2ALMNA | |
| SCHEMBL7814238 | 0.80 | MAPT (0.61) | MAPTALDH1A1USP2TSHRGAA | |
| SCHEMBL7813784 | 0.78 | ALDH1A1 (0.59) | MAPTALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL7812835 | 0.78 | ALDH1A1 (0.59) | MAPTALDH1A1TSHRGAAKMT2A | |
| SCHEMBL9011228 | 0.77 | HSP90AA1 (0.45) | MAPTALDH1A1USP2TSHRKMT2A | |
| SCHEMBL9011007 | 0.77 | KMT2A (0.45) | MAPTALDH1A1USP2TSHRKMT2A | |
| SCHEMBL9011034 | 0.76 | NPSR1 (0.44) | MAPTALDH1A1USP2TSHRKMT2A | |
| SCHEMBL7814104 | 0.75 | KCNA5 (0.58) | MAPTALDH1A1GAAKMT2ALMNA | |
| SCHEMBL7804606 | 0.75 | MAPT (0.63) | MAPTALDH1A1USP2TSHRGAA | |
| SCHEMBL7813660 | 0.69 | MAPT (0.56) | MAPTALDH1A1USP2TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |