Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.52 |
| ▸ | TPSAB1 | Q15661 | 10/20 | 0.52 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9011116 | 0.95 | CCR5 (0.53) | CCR5TPSAB1AVPR1AMEN1KMT2A | |
| SCHEMBL9011078 | 0.89 | CCR5 (0.54) | CCR5AVPR1ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9011020 | 0.88 | CCR5 (0.55) | CCR5TPSAB1AVPR1AMEN1KMT2A | |
| SCHEMBL9011270 | 0.84 | DRD4 (0.59) | CYP1A2 | |
| SCHEMBL9011180 | 0.84 | CCR5 (0.55) | CCR5AVPR1ACYP2D6MEN1KMT2A | |
| SCHEMBL7813354 | 0.84 | CCR5 (0.51) | CCR5TPSAB1AVPR1AMEN1KMT2A | |
| SCHEMBL27295602 | 0.83 | CCR5 (0.66) | CCR5AVPR1AMEN1KMT2AKDM4E | |
| SCHEMBL7817613 | 0.82 | CCR5 (0.51) | CCR5TPSAB1AVPR1AMEN1KMT2A | |
| SCHEMBL9011219 | 0.81 | ALDH1A1 (0.50) | CCR5AVPR1AMEN1KMT2AKDM4E | |
| SCHEMBL9011047 | 0.81 | ALDH1A1 (0.55) | AVPR1ACYP1A2CYP2D6CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |