Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 4/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9011160 | 0.83 | ALDH1A1 (0.52) | PTGDRPTGDR2PTGER2CYP2C9ALDH1A1 | |
| SCHEMBL7811466 | 0.82 | ALDH1A1 (0.49) | PTGDRPTGDR2PTGER2CYP2C9ALDH1A1 | |
| SCHEMBL9011037 | 0.81 | ALDH1A1 (0.52) | PTGDRPTGDR2PTGER2CYP2C9ALDH1A1 | |
| SCHEMBL9011192 | 0.77 | MEN1 (0.51) | PTGDRPTGDR2PTGER2CYP2C9ALDH1A1 | |
| SCHEMBL7804666 | 0.77 | ALDH1A1 (0.54) | PTGDRPTGDR2PTGER2CYP2C9ALDH1A1 | |
| SCHEMBL7813977 | 0.75 | S1PR1 (0.52) | PTGDRPTGDR2PTGER2CYP2C9ALDH1A1 | |
| SCHEMBL6711077 | 0.75 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL7811365 | 0.74 | ALDH1A1 (0.49) | PTGDRPTGDR2PTGER2CYP2C9ALDH1A1 | |
| SCHEMBL9011156 | 0.74 | USP2 (0.66) | ALDH1A1MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL9010984 | 0.72 | PTGDR (0.47) | PTGDRPTGDR2PTGER2CYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |