Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.33 |
| ▸ | MEN1 | O00255 | 6/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.32 |
| ▸ | MAPT | P10636 | 6/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.31 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.31 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1292216 | 0.82 | ACLY (0.37) | TDP1AR | |
| SCHEMBL14844514 | 0.82 | ACLY (0.37) | TDP1AR | |
| SCHEMBL901574 | 0.81 | AR (0.44) | AR | |
| SCHEMBL16572730 | 0.81 | AR (0.32) | L3MBTL1AR | |
| SCHEMBL540303 | 0.80 | CYP3A4 (0.32) | AR | |
| Ammonia Solution, Strong SCHEMBL27989415 | 0.80 | NOTUM (0.32) | MEN1KMT2ASMN1; SMN2AR | |
| SCHEMBL901766 | 0.79 | KDM4E (0.31) | ALDH1A1MAPTNPSR1HPGDKDM4E | |
| SCHEMBL901765 | 0.79 | KDM4E (0.31) | ALDH1A1MAPTNPSR1HPGDKDM4E | |
| SCHEMBL901767 | 0.79 | SMN1; SMN2 (0.36) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL14851127 | 0.79 | PDK2 (0.37) | ALDH1A1MAPTHPGDARKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621897-A1 | IMINE COMPOUNDS | BASF SE (DE) | 2013-08-07 | — | — | EP | disclosed |
| US-20130184320-A1 | Imine Compounds | BASF SE (DE) | 2013-07-18 | — | — | US | disclosed |
| WO-2012042006-A1 | IMINE COMPOUNDS | BASF SE (DE) | 2012-04-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130184320-A1 | Imine Compounds | INMT, PNMT, IPO5 | NPC1 2051/4885RAB9A 1217/4885PKM 582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.