Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9836697 | 0.83 | TSHR (0.39) | ALDH1A1MEN1CYP1A2KMT2ATSHR | |
| SCHEMBL1341696 | 0.83 | ALDH1A1 (0.37) | MCL1ALDH1A1MEN1CYP1A2KMT2A | |
| SCHEMBL3108109 | 0.76 | ALDH1A1 (0.35) | MCL1ALDH1A1TSHR | |
| SCHEMBL2147379 | 0.75 | ALDH1A1 (0.32) | MCL1ALDH1A1TSHR | |
| SCHEMBL3542104 | 0.75 | ALDH1A1 (0.32) | MCL1ALDH1A1MEN1CYP1A2KMT2A | |
| SCHEMBL8164857 | 0.72 | GRM2 (0.32) | ALDH1A1TSHR | |
| SCHEMBL17499002 | 0.71 | — | — | |
| Water SCHEMBL31084442 | 0.70 | MCL1 (0.34) | MCL1ALDH1A1MEN1CYP1A2KMT2A | |
| SCHEMBL4734754 | 0.70 | MCL1 (0.34) | MCL1ALDH1A1MEN1CYP1A2KMT2A | |
| SCHEMBL10882205 | 0.69 | MEN1 (0.30) | ALDH1A1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421946-B1 | 3-indolepyruvic acid derivatives their method of production and therapeutic use | POLIFARMA SPA (IT) | 1996-11-20 | — | — | EP | disclosed |
| EP-0421946-A2 | 3-indolepyruvic acid derivatives their method of production and therapeutic use | POLIFARMA S.p.A. (IT) | 1991-04-10 | — | — | EP | disclosed |