Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1341696 | 0.86 | ALDH1A1 (0.37) | ALDH1A1TSHRMCL1CTSSCTSK | |
| SCHEMBL9836697 | 0.78 | TSHR (0.39) | ALDH1A1TSHRCTSSCTSK | |
| SCHEMBL3542104 | 0.78 | ALDH1A1 (0.32) | ALDH1A1TSHRMCL1 | |
| SCHEMBL9011479 | 0.75 | MCL1 (0.33) | ALDH1A1TSHRMCL1 | |
| SCHEMBL8164857 | 0.75 | GRM2 (0.32) | ALDH1A1TSHRCTSSCTSK | |
| SCHEMBL17499002 | 0.74 | — | — | |
| SCHEMBL4734754 | 0.73 | MCL1 (0.34) | ALDH1A1TSHRMCL1CTSSCTSK | |
| Water SCHEMBL31084442 | 0.73 | MCL1 (0.34) | ALDH1A1TSHRMCL1CTSSCTSK | |
| SCHEMBL3252981 | 0.73 | MCL1 (0.32) | ALDH1A1MCL1CTSSCTSK | |
| SCHEMBL10882205 | 0.72 | MEN1 (0.30) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2542531-B1 | PROCESS FOR SYNTHESIS OF FIPRONIL | GHARDA KEKI HORMUSJI (IN) | 2014-09-17 | — | — | EP | claimed |
| US-8507693-B2 | Process for synthesis of fipronil | Gharda Medical and Advanced Technologies Foundation (IN) | 2013-08-13 | — | — | US | claimed |
| US-20130030190-A1 | PROCESS FOR SYNTHESIS FIPRONIL | Gharda Medical and Advanced Technologies Foundation (IN) | 2013-01-31 | — | — | US | claimed |
| EP-2542531-A1 | PROCESS FOR SYNTHESIS OF FIPRONIL | Gharda, Keki Hormusji (IN) | 2013-01-09 | — | — | EP | claimed |
| CN-102781920-A | Process for synthesizing fipronil | HORMUSJI GHARDA KEKI | 2012-11-14 | — | — | CN | claimed |
| WO-2011107998-A1 | PROCESS FOR SYNTHESIS OF FIPRONIL | GHARDA KEKI HORMUSJI (IN) | 2011-09-09 | — | — | WO | claimed |
| EP-2702039-B1 | A PROCESS FOR PREPARATION OF DICYANOCARBOXYLATE DERIVATIVES | GHARDA KEKI HORMUSJI (IN) | 2017-12-20 | — | — | EP | disclosed |
| US-20170197939-A1 | Tropomyosin-Related Kinase Inhibitors Containing Both A 1H-Pyrazole And A Pyrimidine Moiety | PFIZER INC. (US) | 2017-07-13 | — | — | US | disclosed |
| EP-3131891-A1 | TROPOMYOSIN-RELATED KINASE INHIBITORS CONTAINING BOTH A 1H-PYRAZOLE AND A PYRIMIDINE MOIETY | Pfizer Inc. (US) | 2017-02-22 | — | — | EP | disclosed |
| US-9309190-B2 | Process for preparation of dicyanocarboxylate derivatives | Gharda Medical and Advanced Technologies Foundation (IN) | 2016-04-12 | — | — | US | disclosed |
| WO-2015159175-A1 | TROPOMYOSIN-RELATED KINASE INHIBITORS CONTAINING BOTH A 1H-PYRAZOLE AND A PYRIMIDINE MOIETY | PFIZER INC. (US) | 2015-10-22 | — | — | WO | disclosed |
| CN-102781920-B | Process for synthesizing fipronil | KEKI HORMUSJI GHARDA | 2015-05-20 | — | — | CN | disclosed |
| EP-2542531-B1 | PROCESS FOR SYNTHESIS OF FIPRONIL | GHARDA KEKI HORMUSJI (IN) | 2014-09-17 | — | — | EP | disclosed |
| WO-2012147093-A1 | A PROCESS FOR PREPARATION OF DICYANOCARBOXYLATE DERIVATIVES | GHARDA KEKI HORMUSJI (IN) | 2012-11-01 | — | — | WO | disclosed |
| WO-2011107998-A1 | PROCESS FOR SYNTHESIS OF FIPRONIL | GHARDA KEKI HORMUSJI (IN) | 2011-09-09 | — | — | WO | disclosed |
| WO-2011086570-A1 | PROCESS FOR PREPARATION OF CYANOALKYLPROPIONATE DERIVATIVES | GHARDA KEKI HORMUSJI (IN) | 2011-07-21 | — | — | WO | disclosed |
| EP-1773759-A1 | PROCESS FOR PREPARING SYNTHETIC INTERMEDIATES USEFUL IN PREPARING PYRAZOLE COMPOUNDS | Pfizer Limited (GB) | 2007-04-18 | — | — | EP | disclosed |
| CN-1785966-A | Technology of synthesizing 2,3-dicyano ethyl propionate | LUAN ZHONGYUE (CN) | 2006-06-14 | — | — | CN | disclosed |
| WO-2006003501-A1 | PROCESS FOR PREPARING SYNTHETIC INTERMEDIATES USEFUL IN PREPARING PYRAZOLE COMPOUNDS | PFIZER LIMITED (GB) | 2006-01-12 | — | — | WO | disclosed |
| EP-0295117-B1 | Derivative of a N-phenylpyrazole | RHONE POULENC AGRICULTURE (GB) | 2000-04-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130030190-A1 | PROCESS FOR SYNTHESIS FIPRONIL | FIP1L1, CYP2F1, PFAS | ALDH1A1 918/4885TSHR 539/4885MCL1 1557/4885 |
| US-20170197939-A1 | Tropomyosin-Related Kinase Inhibitors Containing Both A 1H-Pyrazole And A Pyrimidine Moiety | TPM3, MUSK, TPM4 | ALDH1A1 1226/4885TSHR 818/4885MCL1 1107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.