Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 6/20 | 0.49 |
| ▸ | CTSS | P25774 | 5/20 | 0.49 |
| ▸ | CTSB | P07858 | 5/20 | 0.49 |
| ▸ | CTSK | P43235 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | ECE1 | P42892 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9011687 | 0.87 | CTSL (0.49) | CTSLCTSSCTSBCTSKMEN1 | |
| SCHEMBL9011683 | 0.86 | CTSL (0.48) | CTSLCTSSCTSBCTSKMEN1 | |
| SCHEMBL9011676 | 0.84 | CTSL (0.53) | CTSLCTSSCTSBCTSKMEN1 | |
| SCHEMBL9011720 | 0.84 | CTSL (0.53) | CTSLCTSSCTSBCTSKMEN1 | |
| SCHEMBL9012035 | 0.83 | CTSL (0.46) | CTSLCTSSCTSBCTSKCTSD | |
| SCHEMBL9011869 | 0.81 | CTSL (0.49) | CTSLCTSSCTSBCTSKMEN1 | |
| SCHEMBL9011935 | 0.80 | CTSL (0.50) | CTSLCTSSCTSBCTSKMEN1 | |
| SCHEMBL9011684 | 0.76 | LTA4H (0.48) | CTSLCTSSCTSBCTSKMEN1 | |
| SCHEMBL9012148 | 0.75 | CTSB (0.44) | CTSLCTSSCTSBCTSKMEN1 | |
| SCHEMBL15130921 | 0.73 | CTSL (0.72) | CTSLCTSSCTSBCTSKMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545750-A | TREATING HUMAN IMMUNODEFICIENCY VIRUS | ABBOTT LABORATORIES (US) | 1996-08-13 | — | — | US | disclosed |