Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 6/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | PRCP | P42785 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744383 | 0.81 | HDAC8 (0.43) | HDAC8HDAC1HDAC2HDAC3NCOR2 | |
| SCHEMBL3613901 | 0.77 | HDAC8 (0.43) | HDAC8HDAC1HDAC2HDAC3NCOR2 | |
| SCHEMBL18711701 | 0.76 | TRPM8 (0.51) | TRPM8ACKR3ACE | |
| SCHEMBL18711699 | 0.75 | ACE (0.50) | TRPM8ACKR3MEN1ALDH1A1KMT2A | |
| SCHEMBL18701726 | 0.75 | TRPM8 (0.50) | TRPM8ACKR3MEN1KMT2AACE | |
| SCHEMBL18701727 | 0.75 | TRPM8 (0.50) | TRPM8ACKR3MEN1KMT2AACE | |
| SCHEMBL7270808 | 0.74 | CYP2C19 (0.50) | HDAC8MMP1 | |
| SCHEMBL18711706 | 0.74 | RIPK1 (0.49) | HDAC8TRPM8ACKR3MEN1ALDH1A1 | |
| SCHEMBL3609137 | 0.73 | ACE (0.52) | HDAC8HDAC1HDAC2HDAC3NCOR2 | |
| SCHEMBL3610720 | 0.73 | XIAP (0.46) | HDAC8HDAC1HDAC2HDAC3NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545750-A | TREATING HUMAN IMMUNODEFICIENCY VIRUS | ABBOTT LABORATORIES (US) | 1996-08-13 | — | — | US | disclosed |