Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.51 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.51 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5929495 | 0.82 | TSHR (0.67) | TSHRHTTLMNATDP1CYP2C9 | |
| SCHEMBL2551052 | 0.81 | HTT (0.54) | TSHRHTTLMNATDP1CYP2C9 | |
| SCHEMBL28309816 | 0.81 | ALDH1A1 (0.43) | TSHRHTTLMNATDP1CYP2C9 | |
| SCHEMBL5266458 | 0.81 | TSHR (0.70) | TSHRHTTLMNATDP1CYP2C9 | |
| SCHEMBL13212085 | 0.79 | FDPS (0.58) | TSHRHTTLMNATDP1CYP2C9 | |
| SCHEMBL2562138 | 0.78 | HPGD (0.50) | TSHRHTTLMNATDP1SMN1; SMN2 | |
| SCHEMBL29565913 | 0.77 | HPGD (0.58) | TSHRHTTLMNATDP1CYP2C9 | |
| SCHEMBL172302 | 0.77 | TSHR (0.61) | TSHRHTTLMNATDP1CYP2C9 | |
| SCHEMBL9012100 | 0.76 | TSHR (0.47) | TSHRHTTLMNATDP1CYP2C9 | |
| SCHEMBL3655614 | 0.76 | ALDH1A1 (0.52) | TSHRLMNATDP1CYP2C9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5412112-A | Derivatives and preparation of 2,2-dimethyl-5-substituted phenoxy-pentanoic acids | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1995-05-02 | — | — | US | claimed |
| US-5530145-A | ANTICHOLESTEROL AGENTS | SYN-TECH CHEM & PHARM CO., LTD. (TW) | 1996-06-25 | — | — | US | disclosed |
| US-5412112-A | Derivatives and preparation of 2,2-dimethyl-5-substituted phenoxy-pentanoic acids | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1995-05-02 | — | — | US | disclosed |