Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | NCF1 | P14598 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9327590 | 0.89 | TAAR1 (0.36) | TAAR1UTS2RADRA1AHTR1AADRA1D | |
| SCHEMBL6475931 | 0.83 | UTS2R (0.40) | ALDH1A1SMN1; SMN2KDM4ECYP1A2HSD17B10 | |
| SCHEMBL9327521 | 0.83 | ADRA2A (0.39) | ALDH1A1SMN1; SMN2KDM4ECYP1A2CYP2C19 | |
| SCHEMBL9011963 | 0.82 | TAAR1 (0.39) | TAAR1CYP1A2CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL9329867 | 0.80 | ADRA2A (0.32) | UTS2RADRA1AADRA1DADRA1B | |
| SCHEMBL9012178 | 0.78 | ADRA1D (0.34) | ALDH1A1SMN1; SMN2KDM4EUTS2RNCF1 | |
| SCHEMBL9327541 | 0.77 | SMN1; SMN2 (0.39) | ALDH1A1SMN1; SMN2KDM4EHSD17B10UTS2R | |
| SCHEMBL9329006 | 0.77 | ADRA2A (0.33) | ALDH1A1SMN1; SMN2KDM4EUTS2RNCF1 | |
| SCHEMBL9360886 | 0.76 | TAAR1 (0.39) | TAAR1ALDH1A1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL9329176 | 0.75 | ADRA1D (0.40) | ALDH1A1SMN1; SMN2KDM4ECYP1A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523317-A | ADMINISTERING IMIDAZOLE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0633026-A1 | Use of imidazole derivative for antihypertensive agent | NIPPON CHEMIPHAR CO., LTD. (JP) | 1995-01-11 | — | — | EP | disclosed |
| EP-0412529-B1 | Imidazole derivatives, process for the preparation of the same and antiulcer agents containing the same | NIPPON CHEMIPHAR CO (JP) | 1994-03-09 | — | — | EP | disclosed |
| EP-0584588-A1 | Anti-ulcer composition containing imidazole derivative | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-03-02 | — | — | EP | disclosed |
| US-5091403-A | SULFINYL IMIDAZOLE DERIVATIVES AND ANTIULCER AGENTS CONTAINING THE SAME | NIPPON CHEMIPHAR CO., LTD. (JP) | 1992-02-25 | — | — | US | disclosed |
| EP-0412529-A1 | Imidazole derivatives, process for the preparation of the same and antiulcer agents containing the same | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-02-13 | — | — | EP | disclosed |