Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 4/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 3/20 | 0.37 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.34 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9011980 | 0.91 | ADRA1D (0.38) | ADRA1DADRA1AADRA1BADRA2AADRA2C | |
| SCHEMBL9012178 | 0.88 | ADRA1D (0.34) | ADRA1DADRA1AADRA1BADRA2AADRA2C | |
| SCHEMBL9011890 | 0.85 | ADRA1D (0.40) | ADRA1DADRA1AADRA1BADRA2AADRA2C | |
| SCHEMBL6475931 | 0.84 | UTS2R (0.40) | ADRA1AIP6K1UTS2RALDH1A1CYP1A2 | |
| SCHEMBL9329006 | 0.82 | ADRA2A (0.33) | ADRA1DADRA1AADRA1BADRA2AADRA2C | |
| SCHEMBL9327541 | 0.81 | SMN1; SMN2 (0.39) | ADRA1AHTR1AUTS2RALDH1A1HSD17B10 | |
| SCHEMBL9327521 | 0.78 | ADRA2A (0.39) | ADRA1DADRA1AADRA1BADRA2AADRA2C | |
| SCHEMBL9013449 | 0.78 | UTS2R (0.33) | ADRA1DADRA1AADRA1BHTR1AUTS2R | |
| SCHEMBL9012211 | 0.75 | TAAR1 (0.38) | ADRA1DADRA1AADRA1BHTR1AUTS2R | |
| SCHEMBL9329867 | 0.75 | ADRA2A (0.32) | ADRA1DADRA1AADRA1BADRA2AADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0584588-A1 | Anti-ulcer composition containing imidazole derivative | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-03-02 | — | — | EP | disclosed |