Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9013435 | 0.86 | TAAR1 (0.34) | HTR1A | |
| SCHEMBL9012474 | 0.84 | ADRA1A (0.35) | ADRA1AADRA2AGAAHTR1AADRA1D | |
| SCHEMBL27342985 | 0.80 | ADRA2A (0.40) | ADRA1AADRA2AGAA | |
| SCHEMBL6528639 | 0.80 | IDO1 (0.33) | ADRA1AADRA2AADRA1DADRA1B | |
| SCHEMBL9011890 | 0.77 | ADRA1D (0.40) | ADRA1AADRA2AGAANPC1HTR1A | |
| SCHEMBL9012434 | 0.76 | SMN1; SMN2 (0.40) | ADRA1AADRA2AGAA | |
| SCHEMBL9011963 | 0.73 | TAAR1 (0.39) | — | |
| SCHEMBL9011960 | 0.73 | ITK (0.30) | — | |
| SCHEMBL9012324 | 0.72 | PDE3B (0.31) | — | |
| SCHEMBL27358360 | 0.71 | TAAR1 (0.42) | ADRA1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523317-A | ADMINISTERING IMIDAZOLE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0354788-B1 | Novel imidazole derivatives | NIPPON CHEMIPHAR CO (JP) | 1995-09-13 | — | — | EP | disclosed |
| EP-0633026-A1 | Use of imidazole derivative for antihypertensive agent | NIPPON CHEMIPHAR CO., LTD. (JP) | 1995-01-11 | — | — | EP | disclosed |
| EP-0584588-A1 | Anti-ulcer composition containing imidazole derivative | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-03-02 | — | — | EP | disclosed |
| US-5180836-A | Antiulcer agents | NIPPON CHEMIPHAR CO., LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| US-5082943-A | Antiulcer | NIPPON CHEMIPHAR CO., LTD. (JP) | 1992-01-21 | — | — | US | disclosed |
| EP-0354788-A1 | Novel imidazole derivatives | NIPPON CHEMIPHAR CO., LTD. (JP) | 1990-02-14 | — | — | EP | disclosed |