SCHEMBL9012300

SCHEMBL9012300

CC(C)OCCNc1ccccc1C[S+]([O-])c1ncc[nH]1

nearest known ligand 0.32

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.32
NPC1 O15118 1/20 0.32
GAA P10253 1/20 0.32
RAB9A P51151 1/20 0.32
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HSD17B10 Q99714 1/20 0.31
UTS2R Q9UKP6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6475931 0.89 UTS2R (0.40) KDM4EALDH1A1SMN1; SMN2HSD17B10UTS2R
SCHEMBL9011952 0.87 UTS2R (0.37) UTS2R
SCHEMBL9012324 0.84 PDE3B (0.31)
SCHEMBL9327541 0.84 SMN1; SMN2 (0.39) KDM4EGAAALDH1A1MAPK1HTT
SCHEMBL6528639 0.84 IDO1 (0.33)
SCHEMBL9011902 0.82 AR (0.36) NPC1RAB9ASMN1; SMN2
SCHEMBL9011918 0.81 ADRA2A (0.32)
SCHEMBL9011917 0.80
SCHEMBL9012162 0.80 TAAR1 (0.35)
SCHEMBL6483558 0.79 ADRA2A (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5523317-A ADMINISTERING IMIDAZOLE DERIVATIVE NIPPON CHEMIPHAR CO., LTD. (JP) 1996-06-04 US disclosed
EP-0633026-A1 Use of imidazole derivative for antihypertensive agent NIPPON CHEMIPHAR CO., LTD. (JP) 1995-01-11 EP disclosed
EP-0412529-B1 Imidazole derivatives, process for the preparation of the same and antiulcer agents containing the same NIPPON CHEMIPHAR CO (JP) 1994-03-09 EP disclosed
EP-0584588-A1 Anti-ulcer composition containing imidazole derivative NIPPON CHEMIPHAR CO., LTD. (JP) 1994-03-02 EP disclosed
US-5091403-A SULFINYL IMIDAZOLE DERIVATIVES AND ANTIULCER AGENTS CONTAINING THE SAME NIPPON CHEMIPHAR CO., LTD. (JP) 1992-02-25 US disclosed
EP-0412529-A1 Imidazole derivatives, process for the preparation of the same and antiulcer agents containing the same NIPPON CHEMIPHAR CO., LTD. (JP) 1991-02-13 EP disclosed