Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6475931 | 0.89 | UTS2R (0.40) | UTS2RADRA1A | |
| SCHEMBL9012300 | 0.87 | KDM4E (0.32) | UTS2R | |
| SCHEMBL9329023 | 0.86 | VCP (0.32) | UTS2RADRA1AVCP | |
| SCHEMBL9013449 | 0.86 | UTS2R (0.33) | UTS2RADRA1AVCP | |
| SCHEMBL9011932 | 0.85 | PDE3B (0.32) | UTS2R | |
| SCHEMBL9011902 | 0.85 | AR (0.36) | ADRA1A | |
| SCHEMBL9327541 | 0.84 | SMN1; SMN2 (0.39) | UTS2RADRA1A | |
| SCHEMBL9011980 | 0.84 | ADRA1D (0.38) | UTS2RADRA1AVCP | |
| SCHEMBL9327590 | 0.84 | TAAR1 (0.36) | UTS2RADRA1AVCP | |
| SCHEMBL9012324 | 0.82 | PDE3B (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523317-A | ADMINISTERING IMIDAZOLE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0633026-A1 | Use of imidazole derivative for antihypertensive agent | NIPPON CHEMIPHAR CO., LTD. (JP) | 1995-01-11 | — | — | EP | disclosed |
| EP-0412529-B1 | Imidazole derivatives, process for the preparation of the same and antiulcer agents containing the same | NIPPON CHEMIPHAR CO (JP) | 1994-03-09 | — | — | EP | disclosed |
| EP-0584588-A1 | Anti-ulcer composition containing imidazole derivative | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-03-02 | — | — | EP | disclosed |
| US-5091403-A | SULFINYL IMIDAZOLE DERIVATIVES AND ANTIULCER AGENTS CONTAINING THE SAME | NIPPON CHEMIPHAR CO., LTD. (JP) | 1992-02-25 | — | — | US | disclosed |
| EP-0412529-A1 | Imidazole derivatives, process for the preparation of the same and antiulcer agents containing the same | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-02-13 | — | — | EP | disclosed |