Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 8/20 | 0.60 |
| ▸ | ACE | P12821 | 5/20 | 0.56 |
| ▸ | CPA1 | P15085 | 5/20 | 0.56 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.56 |
| ▸ | MMP2 | P08253 | 4/20 | 0.52 |
| ▸ | MMP9 | P14780 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30631191 | 0.91 | MME (0.61) | MMEACECPA1ACE2MMP2 | |
| SCHEMBL6436714 | 0.89 | MMP2 (0.63) | MMEMMP2MMP9ADAMTS4 | |
| SCHEMBL698062 | 0.89 | MMP2 (0.63) | MMEMMP2MMP9ADAMTS4 | |
| Benzene SCHEMBL28198278 | 0.89 | MMP2 (0.63) | MMEMMP2MMP9ADAMTS4 | |
| SCHEMBL698061 | 0.89 | MMP2 (0.63) | MMEMMP2MMP9ADAMTS4 | |
| SCHEMBL13956900 | 0.85 | MMP1 (0.52) | MMP2MMP9ADAMTS4 | |
| SCHEMBL9658885 | 0.84 | KMT2A (0.53) | MMP2MMP9ADAMTS4 | |
| SCHEMBL27445164 | 0.84 | MMP2 (0.57) | MMP2MMP9ADAMTS4 | |
| SCHEMBL16473194 | 0.81 | MMP2 (0.50) | MMP2MMP9ADAMTS4 | |
| SCHEMBL22457647 | 0.81 | MME (0.67) | MMEACECPA1ACE2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743320-A2 | Acyl guanidine and amidine prodrugs | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-11-20 | — | — | EP | disclosed |