Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | IDE | P14735 | 1/20 | 0.50 |
| ▸ | MPI | P34949 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | DDO | Q99489 | 1/20 | 0.46 |
| ▸ | GPR3 | P46089 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10481531 | 0.85 | HTT (0.54) | KDM4EALDH1A1HPGDMAPTIDE | |
| SCHEMBL31514827 | 0.79 | KDM4E (0.46) | KDM4EALDH1A1HPGDMAPTIDE | |
| SCHEMBL6882102 | 0.79 | HTT (0.55) | KDM4EALDH1A1MAPTHSD17B10GAA | |
| SCHEMBL29355024 | 0.79 | KDM4E (0.65) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL1917841 | 0.78 | AHR (0.57) | ALDH1A1HPGDMAPTHSD17B10GAA | |
| Water SCHEMBL11540986 | 0.78 | HTT (0.53) | KDM4EALDH1A1MAPTHSD17B10GAA | |
| SCHEMBL14365065 | 0.77 | CCNB2 (0.50) | KDM4EALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL5479392 | 0.77 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDMAPTIDE | |
| SCHEMBL5459223 | 0.77 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL13437643 | 0.76 | KIF11 (0.46) | KDM4EALDH1A1HPGDMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743317-A2 | Metallocenes comprising a heterocycle and catalysts containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-11-20 | — | — | EP | disclosed |