Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2138325 | 0.84 | ESR1 (0.38) | TAAR1MAPK1POLBESR1ESR2 | |
| SCHEMBL8407090 | 0.81 | TAAR1 (0.43) | TAAR1MAPK1CYP2C19HIF1AALDH1A1 | |
| SCHEMBL5246127 | 0.80 | TAAR1 (0.46) | TAAR1MAPK1CYP2C19HIF1AALDH1A1 | |
| SCHEMBL42933 | 0.75 | SHBG (0.60) | TAAR1MAPK1CYP2C19HIF1AALDH1A1 | |
| SCHEMBL9490072 | 0.74 | TAAR1 (0.41) | TAAR1MAPK1CYP2C19HIF1AALDH1A1 | |
| SCHEMBL11339440 | 0.73 | TAAR1 (0.36) | TAAR1MAPK1CYP2C19HIF1AALDH1A1 | |
| SCHEMBL23511279 | 0.71 | ALDH1A1 (0.46) | TAAR1MAPK1CYP2C19HIF1AALDH1A1 | |
| SCHEMBL17885867 | 0.71 | ALDH1A1 (0.46) | TAAR1MAPK1CYP2C19HIF1AALDH1A1 | |
| SCHEMBL4667150 | 0.71 | ALDH1A1 (0.43) | TAAR1MAPK1CYP2C19HIF1AALDH1A1 | |
| SCHEMBL31590503 | 0.71 | SMN1; SMN2 (0.48) | TAAR1MAPK1CYP2C19HIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743330-A1 | Selectively hydrogenated symmetrical linear block copolymers | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1996-11-20 | — | — | EP | disclosed |
| EP-0434316-A1 | Processes | ZENECA LIMITED (GB) | 1991-06-26 | — | — | EP | disclosed |