Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | MAOA | P21397 | 1/20 | 0.63 |
| ▸ | MAOB | P27338 | 1/20 | 0.63 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | MYC | P01106 | 1/20 | 0.57 |
| ▸ | MAX | P61244 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | MGAM | O43451 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13657861 | 0.91 | AKR1B1 (0.71) | ALDH1A1MAOAMAOBCISD1AKR1B1 | |
| SCHEMBL14560445 | 0.85 | MAOA (0.65) | ALDH1A1MAOAMAOBCISD1AKR1B1 | |
| SCHEMBL24129903 | 0.84 | CISD1 (0.67) | ALDH1A1MAOAMAOBCISD1MEN1 | |
| SCHEMBL2447131 | 0.84 | CISD1 (0.67) | ALDH1A1MAOAMAOBCISD1MEN1 | |
| SCHEMBL2447134 | 0.84 | CISD1 (0.67) | ALDH1A1MAOAMAOBCISD1MEN1 | |
| SCHEMBL3284901 | 0.83 | ENPP2 (0.74) | ALDH1A1MAOAMAOBMEN1KMT2A | |
| SCHEMBL3284905 | 0.83 | ENPP2 (0.74) | ALDH1A1MAOAMAOBMEN1KMT2A | |
| SCHEMBL2622650 | 0.82 | MAOA (0.74) | ALDH1A1MAOAMAOBCISD1HPGD | |
| SCHEMBL15816744 | 0.81 | MAOA (0.69) | MAOAMAOBCISD1AKR1B1MEN1 | |
| SCHEMBL9011343 | 0.81 | AKR1B1 (0.84) | AKR1B1MAPTCA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070078172-A1 | MAO-B INHIBITORS USEFUL FOR TREATING OBESITY | JENRIN DISCOVERY (US) | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078172-A1 | MAO-B INHIBITORS USEFUL FOR TREATING OBESITY | MAOB, MAOA, GPR119 | ALDH1A1 664/4885MAOA 2/4885MAOB 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.