Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PRCP | P42785 | 6/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 7/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7233635 | 0.82 | ADORA1 (0.46) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6957210 | 0.74 | MAOB (0.48) | MEN1KMT2A | |
| SCHEMBL6952914 | 0.74 | MAOB (0.50) | MEN1KMT2A | |
| SCHEMBL6954324 | 0.73 | GSK3B (0.54) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7714682 | 0.72 | ALDH1A1 (0.53) | MEN1KMT2A | |
| SCHEMBL6949510 | 0.72 | ALDH1A1 (0.53) | MEN1KMT2A | |
| SCHEMBL10944422 | 0.72 | CYP2C9 (0.57) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6955433 | 0.71 | CYP2C9 (0.45) | MEN1KMT2A | |
| SCHEMBL5200481 | 0.71 | DRD2 (0.52) | MEN1KMT2ADRD2DRD3 | |
| SCHEMBL6949750 | 0.69 | CYP2C9 (0.43) | MEN1KMT2ADRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565456-A | Anxiolytic aroyl piperidinyl and piperazinylacyl pyrroles | ORTHO PHARMACEUCTICAL CORPORATION (US) | 1996-10-15 | — | — | US | disclosed |
| US-5418236-A | Anxiolytic aroyl piperidinyl and piperazinylacyl pyrroles | ORTHO PHARMACEUTICAL CORPORATION (US) | 1995-05-23 | — | — | US | disclosed |