Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | TNKS | O95271 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9363737 | 0.80 | NPC1 (0.50) | HSP90AA1NPC1RAB9ASMN1; SMN2HRH4 | |
| SCHEMBL13779974 | 0.77 | ALDH1A1 (0.51) | TNKSNPC1RAB9ASMN1; SMN2HRH4 | |
| SCHEMBL24724561 | 0.76 | MEN1 (0.48) | TNKSNPC1RAB9ASMN1; SMN2HRH4 | |
| SCHEMBL30777719 | 0.76 | MEN1 (0.48) | TNKSNPC1RAB9ASMN1; SMN2HRH4 | |
| SCHEMBL9012949 | 0.76 | TRPC6 (0.52) | TNKSNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL424331 | 0.74 | POLB (0.49) | HSP90AA1NPC1RAB9ASMN1; SMN2HRH4 | |
| SCHEMBL20160906 | 0.74 | TDP1 (0.66) | TNKSNPC1RAB9ASMN1; SMN2KDM4A | |
| SCHEMBL9451146 | 0.74 | KMT2A (0.56) | NPC1RAB9ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL2377708 | 0.73 | POLB (0.54) | TNKSNPC1RAB9ASMN1; SMN2KDM4A | |
| SCHEMBL3398915 | 0.73 | CCR8 (0.48) | TNKSNPC1RAB9ASMN1; SMN2KDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532354-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5401734-A | MICROBIOCIDES | FUJISAWA PHAMACEUTICAL CO., LTD. (JP) | 1995-03-28 | — | — | US | disclosed |
| US-5244890-A | Treatment of infectious diseases | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-09-14 | — | — | US | disclosed |
| EP-0345671-A2 | Cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-12-13 | — | — | EP | disclosed |