SCHEMBL9012949

SCHEMBL9012949

CN1CCN(C(=O)c2cc(O)c(OCc3ccccc3)cn2)CC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPC6 Q9Y210 4/20 0.52
NPC1 O15118 3/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
RAB9A P51151 2/20 0.47
ALDH1A1 P00352 1/20 0.47
GAA P10253 1/20 0.47
USP2 O75604 1/20 0.47
HPGD P15428 1/20 0.47
AVPR2 P30518 2/20 0.46
AVPR1A P37288 2/20 0.46
MGLL Q99685 1/20 0.45
PRKAB2 O43741 1/20 0.44
PRKAG1 P54619 1/20 0.44
PRKAA2 P54646 1/20 0.44
PRKAA1 Q13131 1/20 0.44
PRKAG3 Q9UGI9 1/20 0.44
PRKAG2 Q9UGJ0 1/20 0.44
PRKAB1 Q9Y478 1/20 0.44
LRRK2 Q5S007 2/20 0.43
HSD17B10 Q99714 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7760917 0.77 GAA (0.58) NPC1SMN1; SMN2RAB9AALDH1A1GAA
SCHEMBL9012856 0.77 LMNA (0.57) ALDH1A1HPGDHSD17B10KDM4ELMNA
SCHEMBL9013256 0.76 HSP90AA1 (0.48) NPC1SMN1; SMN2RAB9AALDH1A1HPGD
SCHEMBL10322800 0.74 HPGD (0.59) NPC1SMN1; SMN2RAB9AALDH1A1GAA
SCHEMBL14124857 0.73 TRPC6 (0.52) TRPC6NPC1SMN1; SMN2RAB9AHSD17B10
SCHEMBL1577761 0.72 RAB9A (0.56) NPC1SMN1; SMN2RAB9AALDH1A1GAA
SCHEMBL14124829 0.72 TRPC6 (0.54) TRPC6NPC1SMN1; SMN2RAB9A
SCHEMBL167115 0.72 HPGD (0.54) NPC1SMN1; SMN2RAB9AALDH1A1GAA
SCHEMBL1649233 0.71 HPGD (0.56) NPC1SMN1; SMN2RAB9AALDH1A1GAA
SCHEMBL14124853 0.71 P4HTM (0.50) TRPC6SMN1; SMN2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5532354-A ANTIBIOTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-07-02 US disclosed
US-5401734-A MICROBIOCIDES FUJISAWA PHAMACEUTICAL CO., LTD. (JP) 1995-03-28 US disclosed
CN-1025737-C Cephem compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO (JP) 1994-08-24 CN disclosed
US-5244890-A Treatment of infectious diseases FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1993-09-14 US disclosed
CN-1038814-A Cephem compound and preparation method thereof FUJISAWA PHARMACEUTICAL CO (JP) 1990-01-17 CN disclosed
EP-0345671-A2 Cephem compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-12-13 EP disclosed