SCHEMBL9013328

SCHEMBL9013328

CCCCC1(CCCCC2(CCc3ccccc3)CCCCC2)CCCCC1

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.42
OPRL1 P41146 1/20 0.42
SIGMAR1 Q99720 3/20 0.40
CTSL P07711 1/20 0.40
CTSS P25774 1/20 0.40
CTSK P43235 1/20 0.40
CETP P11597 4/20 0.39
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9013676 0.97 SIGMAR1 (0.44) OPRM1OPRL1SIGMAR1CTSLCTSS
SCHEMBL9013715 0.95 KCNH2 (0.43) OPRM1OPRL1SIGMAR1CTSLCTSS
SCHEMBL9013460 0.95 KCNH2 (0.43) OPRM1OPRL1SIGMAR1CTSLCTSS
SCHEMBL9013618 0.95 KCNH2 (0.43) OPRM1OPRL1SIGMAR1CTSLCTSS
SCHEMBL9013280 0.95 KCNH2 (0.43) OPRM1OPRL1SIGMAR1CTSLCTSS
SCHEMBL18092829 0.83 ALDH1A1 (0.41) OPRM1OPRL1SIGMAR1ALDH1A1
SCHEMBL10346520 0.80 ESR1 (0.56) CETPALDH1A1
SCHEMBL9553109 0.79 HRH3 (0.43) ALDH1A1
SCHEMBL25391065 0.76 CETP (0.33) CETP
SCHEMBL25392869 0.76 CETP (0.33) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0568040-B1 Cyclohexane derivative and liquid crystal composition containing the same CHISSO CORP (JP) 1996-12-04 EP disclosed
US-5468421-A Cyclohexane derivative and liquid crystal composition containing the same CHISSO CORPORATION (JP) 1995-11-21 US disclosed
EP-0568040-A1 Cyclohexane derivative and liquid crystal composition containing the same CHISSO CORPORATION (JP) 1993-11-03 EP disclosed