Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | CETP | P11597 | 3/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9013715 | 1.00 | KCNH2 (0.43) | KCNH2SIGMAR1MMP2MMP9MMP8 | |
| SCHEMBL9013280 | 1.00 | KCNH2 (0.43) | KCNH2SIGMAR1MMP2MMP9MMP8 | |
| SCHEMBL9013618 | 1.00 | KCNH2 (0.43) | KCNH2SIGMAR1MMP2MMP9MMP8 | |
| SCHEMBL9013676 | 0.98 | SIGMAR1 (0.44) | KCNH2SIGMAR1MMP2MMP9MMP8 | |
| SCHEMBL9013328 | 0.95 | OPRM1 (0.42) | SIGMAR1CETPOPRM1OPRL1CTSL | |
| SCHEMBL10346520 | 0.85 | ESR1 (0.56) | CETP | |
| SCHEMBL18092829 | 0.82 | ALDH1A1 (0.41) | SIGMAR1OPRM1OPRL1 | |
| SCHEMBL9553109 | 0.81 | HRH3 (0.43) | — | |
| SCHEMBL25392990 | 0.79 | TSHR (0.40) | CETP | |
| SCHEMBL25392860 | 0.79 | TSHR (0.40) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0568040-B1 | Cyclohexane derivative and liquid crystal composition containing the same | CHISSO CORP (JP) | 1996-12-04 | — | — | EP | disclosed |
| US-5468421-A | Cyclohexane derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1995-11-21 | — | — | US | disclosed |