Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9013761 | 0.87 | ALDH1A1 (0.32) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL8908483 | 0.78 | CYP2D6 (0.34) | ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL8119768 | 0.74 | TSHR (0.37) | ALDH1A1HSD17B10HPGDNPC1RAB9A | |
| SCHEMBL2527313 | 0.73 | ALDH1A1 (0.34) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL9034935 | 0.73 | ALDH1A1 (0.31) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL6771920 | 0.72 | HDAC4 (0.35) | ALDH1A1NPC1RAB9AL3MBTL1PLA2G1B | |
| SCHEMBL8651188 | 0.68 | HTR2A (0.33) | ALOX15HPGD | |
| SCHEMBL1134714 | 0.66 | ALDH1A1 (0.46) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL29816195 | 0.66 | ALDH1A1 (0.46) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL3378773 | 0.66 | CA1 (0.39) | ALDH1A1ALOX15HSD17B10HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536745-A | (Hetero)-aryl ketones derivatives with antibacterial properties | SMITHKLINE BEECHAM P.L.C. (GB) | 1996-07-16 | — | — | US | disclosed |
| EP-0652875-A1 | (HETERO)-ARYL KETONES DERIVATIVES WITH ANTIBACTERIAL PROPERTIES | SMITHKLINE BEECHAM PLC (GB) | 1995-05-17 | — | — | EP | disclosed |
| WO-1994002478-A1 | (HETERO)-ARYL KETONES DERIVATIVES WITH ANTIBACTERIAL PROPERTIES | SMITHKLINE BEECHAM PLC (GB) | 1994-02-03 | — | — | WO | disclosed |