Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6771920 | 0.79 | HDAC4 (0.35) | ALDH1A1NPC1RAB9AKIF11 | |
| SCHEMBL8113711 | 0.77 | LMNA (0.40) | TSHRATMGPR35LMNATYR | |
| SCHEMBL9013399 | 0.74 | ALDH1A1 (0.32) | ALDH1A1NPC1MAPTHPGDRAB9A | |
| SCHEMBL9013761 | 0.74 | ALDH1A1 (0.32) | ALDH1A1NPC1HPGDRAB9AHSD17B10 | |
| SCHEMBL4448406 | 0.73 | ATM (0.42) | TSHRATMGPR35LMNATYR | |
| SCHEMBL9128696 | 0.73 | — | — | |
| SCHEMBL8762246 | 0.72 | TSHR (0.48) | TSHRLMNATYRNR1H4GRIA4 | |
| SCHEMBL1627214 | 0.72 | LMNA (0.35) | TSHRATMGPR35LMNATYR | |
| SCHEMBL5165570 | 0.70 | SRD5A2 (0.46) | TSHRLMNANR1H4ALDH1A1NPC1 | |
| SCHEMBL8545831 | 0.70 | TSHR (0.46) | TSHRATMGPR35LMNATYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020434-A1 | 3-AMIDINOANILINE DERIVATIVES, ACTIVATED BLOOD COAGULATION FACTOR X INHIBITORS, AND INTERMEDIATES FOR PRODUCING BOTH | Kissei Pharmaceutical Co., Ltd. (JP) | 2000-07-19 | — | — | EP | disclosed |
| US-5246944-A | Hypotensive and anxiolytic agents; antidepressants | MERCK & CO., INC. (US) | 1993-09-21 | — | — | US | disclosed |
| EP-0527534-A1 | Quinoline and azaquinoline angiotensin II antagonists | MERCK & CO. INC. (US) | 1993-02-17 | — | — | EP | disclosed |