Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9013225 | 0.81 | KMT2A (0.40) | KMT2AMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5608545 | 0.76 | KMT2A (0.34) | KMT2A | |
| SCHEMBL125935 | 0.69 | CYP3A4 (0.41) | KMT2AMAPTALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL248738 | 0.69 | CYP3A4 (0.41) | KMT2AMAPTALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL4307871 | 0.69 | HSP90AA1 (0.53) | KMT2AMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL8556307 | 0.69 | POLB (0.37) | KMT2AMAPTALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL28084277 | 0.68 | CYP3A4 (0.40) | KMT2AMAPTALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL2882316 | 0.68 | SERPINE1 (0.46) | KMT2AMAPTALDH1A1SMN1; SMN2POLB | |
| SCHEMBL29871279 | 0.68 | CYP3A4 (0.39) | KMT2AMAPTALDH1A1MAPK1SMN1; SMN2 | |
| Phosphine SCHEMBL18982856 | 0.68 | CYP3A4 (0.39) | KMT2AMAPTALDH1A1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563266-A | Method of use of disubstituted monochlorotriazines | GENERAL ELECTRIC COMPANY (US) | 1996-10-08 | — | — | US | claimed |
| US-5446155-A | Reacting monoorganoxy dichloro-triazine with monohydroxy aliphatic compound in non-polar solvent and aqueous alkali metal hydroxide solution with the presence of phase transfer catalysts | GENERAL ELECTRIC COMPANY (US) | 1995-08-29 | — | — | US | claimed |
| EP-0592143-A1 | Method for preparing disubstituted monochlorotriazines | GENERAL ELECTRIC COMPANY (US) | 1994-04-13 | — | — | EP | claimed |
| US-5563266-A | Method of use of disubstituted monochlorotriazines | GENERAL ELECTRIC COMPANY (US) | 1996-10-08 | — | — | US | disclosed |
| US-5446155-A | Reacting monoorganoxy dichloro-triazine with monohydroxy aliphatic compound in non-polar solvent and aqueous alkali metal hydroxide solution with the presence of phase transfer catalysts | GENERAL ELECTRIC COMPANY (US) | 1995-08-29 | — | — | US | disclosed |
| EP-0592143-A1 | Method for preparing disubstituted monochlorotriazines | GENERAL ELECTRIC COMPANY (US) | 1994-04-13 | — | — | EP | disclosed |