SCHEMBL5608545

SCHEMBL5608545

CCC(CC)(COP(=O)(O)O)Oc1nc(Cl)nc(OC(=O)c2c(C)cc(C)cc2C)n1

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8523101 0.84 HSP90AA1 (0.34)
SCHEMBL9013436 0.76 KMT2A (0.50) KMT2A
SCHEMBL8523654 0.76 S1PR1 (0.32)
SCHEMBL9013225 0.70 KMT2A (0.40) KMT2A
SCHEMBL9288292 0.67 HSP90AA1 (0.43)
SCHEMBL9576057 0.61 TAS1R3 (0.39) KMT2A
SCHEMBL28522828 0.60 CYP3A4 (0.40) KMT2A
SCHEMBL28929367 0.59 TAS1R3 (0.38) KMT2A
SCHEMBL22159585 0.59 TAS1R3 (0.38) KMT2A
Water SCHEMBL9576110 0.59 TAS1R3 (0.38) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1242537-B1 POLY(PHENYLENE ETHER)-POLYAMIDE RESIN BLENDS, METHOD OF MANUFACTURE GEN ELECTRIC (US) 2007-03-07 EP disclosed
EP-1242537-A1 POLY(PHENYLENE ETHER)-POLYAMIDE RESIN BLENDS, METHOD, AND ARTICLES MADE THEREFROM GENERAL ELECTRIC COMPANY (US) 2002-09-25 EP disclosed
US-6362263-B1 LOW TEMPERATURE IMPACT STRENGTH GENERAL ELECTRIC COMPANY 2002-03-26 US disclosed
WO-2001042364-A1 POLY(PHENYLENE ETHER)-POLYAMIDE RESIN BLENDS, METHOD, AND ARTICLES MADE THEREFROM GENERAL ELECTRIC COMPANY (US) 2001-06-14 WO disclosed
EP-0776940-A2 Compatibilized polyphenylene ether-polyamide compositions GENERAL ELECTRIC COMPANY (US) 1997-06-04 EP disclosed