SCHEMBL2882316

SCHEMBL2882316

Cc1cc(C)c(C(=O)Oc2ccccc2OC(=O)c2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SERPINE1 P05121 1/20 0.46
KMT2A Q03164 6/20 0.42
ABCB1 P08183 1/20 0.42
MEN1 O00255 4/20 0.41
ESR1 P03372 2/20 0.41
ESR2 Q92731 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
ALDH1A1 P00352 1/20 0.40
POLB P06746 2/20 0.40
MAPT P10636 2/20 0.39
KDM4E B2RXH2 1/20 0.39
LMNA P02545 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28107920 0.93 ABCB1 (0.48) KMT2AABCB1MEN1SMN1; SMN2ALDH1A1
SCHEMBL31321711 0.89 POLB (0.49) KMT2AMEN1ESR1ESR2ALDH1A1
SCHEMBL28916583 0.89 SERPINE1 (0.38) SERPINE1KMT2AABCB1MEN1ESR1
SCHEMBL28234807 0.87 KMT2A (0.47) KMT2AABCB1MEN1ESR1ESR2
SCHEMBL28395181 0.85 KMT2A (0.36) SERPINE1KMT2AABCB1MEN1ESR1
SCHEMBL2881873 0.85 L3MBTL1 (0.43) KMT2ASMN1; SMN2ALDH1A1MAPTCYP1A2
SCHEMBL9282972 0.83 MAPT (0.49) KMT2AMEN1SMN1; SMN2ALDH1A1POLB
Phosphine SCHEMBL28088577 0.81 MAPT (0.48) KMT2AMEN1SMN1; SMN2ALDH1A1POLB
SCHEMBL31321615 0.81 ACHE (0.53) KMT2AALDH1A1MAPTKDM4E
SCHEMBL17502668 0.81 LMNA (0.47) KMT2AMEN1ESR1ESR2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114085301-B Solid catalyst component for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2023-05-09 CN claimed
US-9464144-B2 Enhanced procatalyst composition and process W. R. Grace & Co.—Conn. (US) 2016-10-11 US claimed
CN-114085301-B Solid catalyst component for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2023-05-09 CN disclosed
US-9464144-B2 Enhanced procatalyst composition and process W. R. Grace & Co.—Conn. (US) 2016-10-11 US disclosed
US-9464144-B2 Enhanced procatalyst composition and process W. R. Grace & Co.—Conn. (US) 2016-10-11 US disclosed
US-9464144-B2 Enhanced procatalyst composition and process W. R. Grace & Co.—Conn. (US) 2016-10-11 US disclosed
EP-2373701-B1 ENHANCED PROCATALYST COMPOSITION AND PROCESS GRACE W R & CO (US) 2016-03-09 EP disclosed
EP-2373701-B1 ENHANCED PROCATALYST COMPOSITION AND PROCESS GRACE W R & CO (US) 2016-03-09 EP disclosed
US-20140274668-A1 ENHANCED PROCATALYST COMPOSITION AND PROCESS W. R. GRACE & CO.-CONN. (US) 2014-09-18 US disclosed
US-20140274668-A1 ENHANCED PROCATALYST COMPOSITION AND PROCESS W. R. GRACE & CO.-CONN. (US) 2014-09-18 US disclosed
US-20140274668-A1 ENHANCED PROCATALYST COMPOSITION AND PROCESS W. R. GRACE & CO.-CONN. (US) 2014-09-18 US disclosed
US-8604235-B2 Production of substituted phenylene aromatic diesters and compositions DOW GLOBAL TECHNOLOGIES LLC (US) 2013-12-10 US disclosed
US-20100204506-A1 Production of Substituted Phenylene Aromatic Diesters and Compositions W. R. GRACE & CO.-CONN. 2010-08-12 US disclosed
US-20100204506-A1 Production of Substituted Phenylene Aromatic Diesters and Compositions W. R. GRACE & CO.-CONN. 2010-08-12 US disclosed
US-20100204506-A1 Production of Substituted Phenylene Aromatic Diesters and Compositions W. R. GRACE & CO.-CONN. 2010-08-12 US disclosed
WO-2010078519-A1 PRODUCTION OF SUBSTITUTED PHENYLENE AROMATIC DIESTERS DOW GLOBAL TECHNOLOGIES INC. (US) 2010-07-08 WO disclosed
US-20100173769-A1 Enhanced Procatalyst Composition and Process W. R. GRACE & CO.-CONN. 2010-07-08 US disclosed
US-20100173769-A1 Enhanced Procatalyst Composition and Process W. R. GRACE & CO.-CONN. 2010-07-08 US disclosed
US-20100173769-A1 Enhanced Procatalyst Composition and Process W. R. GRACE & CO.-CONN. 2010-07-08 US disclosed
WO-2010078503-A1 ENHANCED PROCATALYST COMPOSITION AND PROCESS DOW GLOBAL TECHNOLOGIES INC. (US) 2010-07-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100204506-A1 Production of Substituted Phenylene Aromatic Diesters and Compositions PAH, DDC, DDT SERPINE1 4884/4885KMT2A 1611/4885ABCB1 3111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.