Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | UPP1 | Q16831 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11235934 | 0.88 | KDM4E (0.45) | KDM4EMEN1KMT2AMAPTTHRB | |
| SCHEMBL11228910 | 0.82 | KDM4E (0.48) | KDM4EMEN1KMT2AMAPTTHRB | |
| SCHEMBL11042949 | 0.78 | KDM4E (0.53) | KDM4EMEN1KMT2AMAPTTHRB | |
| SCHEMBL4801774 | 0.77 | KDM4E (0.55) | KDM4EMEN1KMT2AMAPTTHRB | |
| SCHEMBL10962110 | 0.76 | KDM4E (0.51) | KDM4EMEN1KMT2AMAPTTHRB | |
| SCHEMBL8043774 | 0.76 | KDM4E (0.50) | KDM4EMEN1KMT2AMAPTTHRB | |
| SCHEMBL11238930 | 0.75 | LMNA (0.43) | KDM4EMEN1KMT2AMAPTTHRB | |
| SCHEMBL5365754 | 0.75 | KDM4E (0.49) | KDM4EMEN1KMT2AMAPTTHRB | |
| SCHEMBL9013810 | 0.75 | IDH1 (0.31) | KDM4EMEN1KMT2AMAPTTHRB | |
| Hydrochloric Acid SCHEMBL11508335 | 0.74 | ALDH1A1 (0.34) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471454-B1 | Reactive pyridone azo dyestuffs | ZENECA LTD (GB) | 1996-12-04 | — | — | EP | disclosed |
| US-5175261-A | Useful for coloring cellulose materials, animal furs or leather | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-12-29 | — | — | US | disclosed |