Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.40 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.40 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 8/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8789829 | 0.83 | MAPT (0.39) | TXNRD1TXNRD3TXNRD2APPABCC8 | |
| SCHEMBL8789881 | 0.77 | MYC (0.50) | MYCWDR5ALDH1A1HPGD | |
| SCHEMBL8788935 | 0.77 | MYC (0.50) | MYCWDR5ALDH1A1MEN1KMT2A | |
| SCHEMBL8789362 | 0.77 | ERBB2 (0.40) | MYCWDR5ALDH1A1MEN1KMT2A | |
| SCHEMBL9013799 | 0.75 | MYC (0.35) | MYCWDR5MAPTALDH1A1HPGD | |
| SCHEMBL8790492 | 0.74 | MYC (0.53) | MYCWDR5MAPK1POLBRAB9A | |
| SCHEMBL7291266 | 0.69 | MAPT (0.50) | MAPTALDH1A1MEN1KMT2APKM | |
| SCHEMBL16984816 | 0.68 | ALDH1A1 (0.45) | TXNRD1TXNRD3TXNRD2APPMAPT | |
| SCHEMBL8789920 | 0.67 | ADORA1 (0.44) | MYCWDR5SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL4468508 | 0.66 | ALDH1A1 (0.46) | APPMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996019467-A1 | SUBSTITUTED THIADIAZOLES, COMPOSITIONS CONTAINING THEM AND THEIR USE AS ANTIMICROBIAL AND MARINE ANTIFOULING AGENTS | THE DOW CHEMICAL COMPANY (US) | 1996-06-27 | — | — | WO | disclosed |
| US-5488060-A | Substituted thiadiazoles, compositions containing them and their use as antimicrobial and marine antifouling agents | THE DOW CHEMICAL COMPANY (US) | 1996-01-30 | — | — | US | disclosed |