Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 9/20 | 0.35 |
| ▸ | WDR5 | P61964 | 9/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.32 |
| ▸ | GCGR | P47871 | 2/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8789633 | 0.81 | MYC (0.50) | MYCWDR5ALDH1A1MAPTKDM4E | |
| SCHEMBL8788935 | 0.81 | MYC (0.50) | MYCWDR5ALDH1A1 | |
| SCHEMBL8789881 | 0.81 | MYC (0.50) | MYCWDR5ALDH1A1HPGD | |
| SCHEMBL8789362 | 0.80 | ERBB2 (0.40) | MYCWDR5ALDH1A1MAPK14KDM4E | |
| SCHEMBL8792575 | 0.78 | PTGS2 (0.41) | MYCWDR5PTGS1PTGS2 | |
| SCHEMBL8790492 | 0.77 | MYC (0.53) | MYCWDR5KDM4E | |
| SCHEMBL9013737 | 0.75 | MYC (0.40) | MYCWDR5ALDH1A1MAPTKDM4E | |
| SCHEMBL8789377 | 0.71 | IDO1 (0.42) | ALDH1A1MAPTCYP11B1CYP11B2KDM4E | |
| SCHEMBL8789920 | 0.70 | ADORA1 (0.44) | MYCWDR5KDM4ETSHR | |
| SCHEMBL19605694 | 0.69 | MAPT (0.58) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996019467-A1 | SUBSTITUTED THIADIAZOLES, COMPOSITIONS CONTAINING THEM AND THEIR USE AS ANTIMICROBIAL AND MARINE ANTIFOULING AGENTS | THE DOW CHEMICAL COMPANY (US) | 1996-06-27 | — | — | WO | disclosed |
| US-5488060-A | Substituted thiadiazoles, compositions containing them and their use as antimicrobial and marine antifouling agents | THE DOW CHEMICAL COMPANY (US) | 1996-01-30 | — | — | US | disclosed |