Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 8/20 | 0.50 |
| ▸ | WDR5 | P61964 | 8/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8789881 | 0.83 | MYC (0.50) | MYCWDR5ERBB2ADORA1ADORA2A | |
| SCHEMBL8789633 | 0.83 | MYC (0.50) | MYCWDR5ERBB2KMT2ANPSR1 | |
| SCHEMBL8789362 | 0.83 | ERBB2 (0.40) | MYCWDR5ERBB2ADORA1ADORA2A | |
| SCHEMBL8790492 | 0.83 | MYC (0.53) | MYCWDR5ADORA1NPC1RAB9A | |
| SCHEMBL9013799 | 0.81 | MYC (0.35) | MYCWDR5ALDH1A1 | |
| SCHEMBL8789358 | 0.80 | MYC (0.39) | MYCWDR5ERBB2ADORA1ADORA2A | |
| SCHEMBL8792575 | 0.77 | PTGS2 (0.41) | MYCWDR5 | |
| SCHEMBL27081216 | 0.75 | RAB9A (0.41) | MYCWDR5ERBB2ADORA2AKMT2A | |
| SCHEMBL8789377 | 0.73 | IDO1 (0.42) | ADORA1ADORA2ACYP1A2ALDH1A1LMNA | |
| SCHEMBL8789920 | 0.72 | ADORA1 (0.44) | MYCWDR5ADORA1ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799216-A1 | SUBSTITUTED THIADIAZOLES, COMPOSITIONS CONTAINING THEM AND THEIR USE AS ANTIMICROBIAL AND MARINE ANTIFOULING AGENTS | THE DOW CHEMICAL COMPANY (US) | 1997-10-08 | — | — | EP | disclosed |
| WO-1996019467-A1 | SUBSTITUTED THIADIAZOLES, COMPOSITIONS CONTAINING THEM AND THEIR USE AS ANTIMICROBIAL AND MARINE ANTIFOULING AGENTS | THE DOW CHEMICAL COMPANY (US) | 1996-06-27 | — | — | WO | disclosed |
| US-5488060-A | Substituted thiadiazoles, compositions containing them and their use as antimicrobial and marine antifouling agents | THE DOW CHEMICAL COMPANY (US) | 1996-01-30 | — | — | US | disclosed |