Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11417448 | 0.84 | GFER (0.51) | MAPTSMN1; SMN2TP53POLBLMNA | |
| SCHEMBL11506912 | 0.82 | SMN1; SMN2 (0.50) | MAPTSMN1; SMN2TP53LMNAALDH1A1 | |
| SCHEMBL11670573 | 0.80 | MTNR1A (0.46) | MAPTSMN1; SMN2TP53POLBLMNA | |
| SCHEMBL11136662 | 0.80 | GFER (0.46) | MAPTTP53LMNAALDH1A1HPGD | |
| SCHEMBL6365445 | 0.79 | MTNR1A (0.54) | MAPTSMN1; SMN2LMNAALDH1A1HTT | |
| SCHEMBL9349279 | 0.78 | MTNR1A (0.53) | SMN1; SMN2ALDH1A1TSHRMTNR1AMTNR1B | |
| SCHEMBL7595655 | 0.78 | KMT2A (0.45) | LMNAALDH1A1MTNR1AMTNR1BACHE | |
| SCHEMBL2068905 | 0.78 | GFER (0.45) | MAPTSMN1; SMN2TP53LMNAALDH1A1 | |
| SCHEMBL397442 | 0.77 | GFER (0.54) | MAPTSMN1; SMN2TP53LMNAALDH1A1 | |
| SCHEMBL11212465 | 0.77 | TDP1 (0.45) | MAPTSMN1; SMN2TP53LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5550218-A | DISPERSE DYES FOR DYEING OR PRINTING TEXTILE MATERIALS MADES OF NATURAL, SYNTHETIC OR SEMI-SYNTHETIC HYDROPHOBIC ORGANIC MATERIALS | SANDOZ LTD. (CH) | 1996-08-27 | — | — | US | disclosed |