Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 10/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11242342 | 0.85 | KMT2A (0.56) | KMT2AMTNR1AMTNR1BCYP3A4LMNA | |
| SCHEMBL7819158 | 0.81 | ALDH1A1 (0.61) | KMT2AMTNR1AMTNR1BCYP3A4LMNA | |
| SCHEMBL11417448 | 0.81 | GFER (0.51) | KMT2ACYP3A4LMNAMEN1KDM4E | |
| SCHEMBL27993892 | 0.80 | ALDH1A1 (0.41) | KMT2AMTNR1AMTNR1BCYP3A4LMNA | |
| SCHEMBL11424229 | 0.80 | POLB (0.47) | KMT2AMTNR1AMTNR1BMEN1ALDH1A1 | |
| SCHEMBL9059920 | 0.79 | CYP3A4 (0.51) | KMT2AMTNR1AMTNR1BCYP3A4LMNA | |
| SCHEMBL7038319 | 0.79 | MEN1 (0.49) | KMT2ALMNAMEN1KDM4EALDH1A1 | |
| SCHEMBL6365445 | 0.79 | MTNR1A (0.54) | MTNR1AMTNR1BLMNAKDM4EALDH1A1 | |
| SCHEMBL8415550 | 0.78 | LMNA (0.48) | KMT2AMTNR1AMTNR1BCYP3A4LMNA | |
| SCHEMBL9013746 | 0.78 | MAPT (0.46) | KMT2AMTNR1AMTNR1BLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1002020-B1 | DYE INTERMEDIATE AND METHOD TO MANUFACTURE DYES | AMERSHAM PLC (GB) | 2002-11-06 | — | — | EP | disclosed |
| US-6458966-B1 | Dye intermediate and method | NYCOMED AMERSHAM PLC (GB) | 2002-10-01 | — | — | US | disclosed |
| EP-1002020-A1 | DYE INTERMEDIATE AND METHOD TO MANUFACTURE DYES | Nycomed Amersham plc (GB) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999007793-A1 | DYE INTERMEDIATE AND METHOD TO MANUFACTURE DYES | NYCOMED AMERSHAM PLC (GB) | 1999-02-18 | — | — | WO | disclosed |