Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 12/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8475279 | 0.85 | KMT2A (0.60) | MEN1KMT2AGAAHCRTR1LMNA | |
| SCHEMBL8475297 | 0.84 | GAA (0.64) | MEN1KMT2AGAAHCRTR1LMNA | |
| SCHEMBL9013933 | 0.84 | KMT2A (0.53) | MEN1KMT2AGAAHCRTR1LMNA | |
| SCHEMBL8660441 | 0.83 | MEN1 (0.50) | MEN1KMT2AGAAHCRTR1CYP3A4 | |
| SCHEMBL9013742 | 0.82 | MEN1 (0.46) | MEN1KMT2AGAAHCRTR1LMNA | |
| SCHEMBL6031707 | 0.80 | KMT2A (0.54) | MEN1KMT2AGAAHCRTR1LMNA | |
| SCHEMBL8475522 | 0.80 | FAAH (0.49) | MEN1KMT2AGAAHCRTR1LMNA | |
| SCHEMBL8695358 | 0.80 | GAA (0.45) | MEN1KMT2AGAAHCRTR1LMNA | |
| SCHEMBL8662135 | 0.79 | GAA (0.44) | MEN1KMT2AGAAHCRTR1LMNA | |
| SCHEMBL8665062 | 0.79 | MEN1 (0.62) | MEN1KMT2AGAAHCRTR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554607-A | INCREASING HDL CHOLESTEROL | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-09-10 | — | — | US | claimed |
| US-5554607-A | INCREASING HDL CHOLESTEROL | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-09-10 | — | — | US | disclosed |