SCHEMBL9013874

SCHEMBL9013874

C=CC[C@H]1CC[C@H](CCCCC2CCC(=O)CC2)CC1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 2/20 0.32
NOS1 P29475 2/20 0.32
NOS2 P35228 2/20 0.32
PRSS1 P07477 2/20 0.30
CTRC Q99895 2/20 0.30
F2 P00734 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9013881 1.00 NOS3 (0.32) NOS3NOS1NOS2PRSS1CTRC
SCHEMBL9354085 0.92 NOS3 (0.33) NOS3NOS1NOS2PRSS1CTRC
SCHEMBL9354075 0.92 NOS3 (0.33) NOS3NOS1NOS2PRSS1CTRC
SCHEMBL571633 0.88 NOS3 (0.37) NOS3NOS1NOS2PRSS1CTRC
SCHEMBL7912246 0.84 SIGMAR1 (0.34) NOS3NOS1NOS2
SCHEMBL7912234 0.84 SIGMAR1 (0.34) NOS3NOS1NOS2
SCHEMBL8858069 0.81 NOS3 (0.33) NOS3NOS1NOS2PRSS1CTRC
SCHEMBL8858074 0.81 NOS3 (0.33) NOS3NOS1NOS2PRSS1CTRC
SCHEMBL11009414 0.80 SIGMAR1 (0.39)
Ethylene SCHEMBL10406744 0.79 NOS3 (0.36) NOS3NOS1NOS2PRSS1CTRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5310605-A None JP disclosed
EP-0568040-B1 Cyclohexane derivative and liquid crystal composition containing the same CHISSO CORP (JP) 1996-12-04 EP disclosed
US-5468421-A Cyclohexane derivative and liquid crystal composition containing the same CHISSO CORPORATION (JP) 1995-11-21 US disclosed
JP-H05310605-A CYCLOHEXANE DERIVATIVE CHISSO CORP 1993-11-22 JP disclosed
EP-0568040-A1 Cyclohexane derivative and liquid crystal composition containing the same CHISSO CORPORATION (JP) 1993-11-03 EP disclosed