Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.52 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.52 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 2/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | IKBKB | O14920 | 1/20 | 0.47 |
| ▸ | OXTR | P30559 | 2/20 | 0.47 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9014030 | 0.98 | CASP6 (0.51) | CASP6GFERCYP4F2CYP4A11CHEK2 | |
| SCHEMBL16823226 | 0.91 | NAMPT (0.53) | CASP6GFERCYP4F2CYP4A11CHEK2 | |
| SCHEMBL16532744 | 0.91 | NAMPT (0.53) | CASP6GFERCYP4F2CYP4A11CHEK2 | |
| SCHEMBL16220677 | 0.87 | EPHX2 (0.56) | CYP4F2CYP4A11CHEK2NAMPTHRH3 | |
| SCHEMBL18672909 | 0.86 | MEN1 (0.56) | CYP4F2CYP4A11CHEK2NAMPTHRH3 | |
| SCHEMBL24596887 | 0.86 | CYP4F2 (0.51) | CYP4F2CYP4A11CHEK2NAMPTHRH3 | |
| SCHEMBL2096831 | 0.86 | EPHX2 (0.55) | CYP4F2CYP4A11CHEK2NAMPT | |
| SCHEMBL31370640 | 0.86 | ALDH1A1 (0.55) | CYP4F2CYP4A11CHEK2NAMPTHRH3 | |
| SCHEMBL213590 | 0.85 | SRD5A1 (0.50) | HRH3KMT2ASRD5A1PARP10SRD5A2 | |
| SCHEMBL14413530 | 0.85 | PARP10 (0.50) | CHEK2HRH3KMT2ASRD5A1PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022146201-A1 | EPIDERMAL GROWTH FACTOR RECEPTOR INHIBITORS | JOINT STOCK COMPANY "BIOCAD" (RU) | 2022-07-07 | — | — | WO | disclosed |
| WO-2011142359-A1 | SPIRO COMPOUND AND DRUG FOR ACTIVATING ADIPONECTIN RECEPTOR | 日産化学工業株式会社 (JP) | 2011-11-17 | — | — | WO | disclosed |
| US-5580883-A | INHIBITING DEGENERATION AND NECROCYTOSIS OF CEREBRAL NERVE CELLS CAUSED BY OXIDATIVE STRESS INDUCING GLUTAMIC ACID IN MAMMALS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-03 | — | — | US | disclosed |
| EP-0449195-B1 | Aminobenzene compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-05-08 | — | — | EP | disclosed |
| EP-0449195-A2 | Aminobenzene compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-10-02 | — | — | EP | disclosed |